Seeking men and women to help assess how well a specific drug called INT-787 works in participants with severe alcohol-associated hepatitis (sAH).
Seeking men and women with Systemic Lupus Erythematous(SLE) and Lupus Nephritis for a biorepository study to collect health information and biological samples to help researchers learn more about the disease and help design future studies.
Seeking adults diagnosed with skin-limited lupus (cutaneous lupus erythematosus or CLE) for a study collecting blood and skin samples to better predict the risk of progression to systemic disease (systemic lupus erythematosus or SLE).
Seeking people with a bleeding disorder such as Hemophilia or Von Willebrand Disease for a registry to collect health data to address the needs and challenges of people living with bleeding disorders.
Seeking men & women over 18 years old who have a blood disorder or malignancy to investigate normal and abnormal cell growth.
Men and women over 16 years old undergoing transplantation with unlicensed CBUs (cord blood units) will be enrolled. Cord blood units not meeting FDA requirements or not yet approved by the FDA may be used for transplant if the transplant is done as part of a study.
Adult male and female U.S. recipients of allogeneic or autologous HSC transplants or cellular therapies are eligible to participate in the NMDP Research Sample Repository.
Seeking people diagnosed with Chronic Fatigue Syndrome, Long COVID, Chronic Lyme, Fibromyalgia, Gulf-War Illness, Hypermobile EDS or Hypermobility Syndrome, Postural orthostatic tachycardia syndrome (POTS),or Orthostatic Intolerance for a study collecting blood, urine, saliva and skin tissue.
Seeking boys aged 6-14 years old who have previously been treated with adeno-associated virus (AAV) based gene therapy for a study of an investigational drug
Seeking boys and men aged 12-50 with Becker Muscular Dystrophy for a study of the safety and effectiveness of an investigational drug to prevent muscle weakness.
Seeking boys aged 4 to 16 for a study of an investigational drug to increase dystrophin protein levels in muscles.
Seeking men and women with upper limb spasticity that affects the movement in their arms and/or hands for a study comparing two treatments that have already been approved by the Food and Drug Administration (FDA).
Seeking adults aged 18 and older who either have Facioscapulohumeral Muscular Dystrophy (FSHD) or are healthy volunteers for a study to identify genetic biomarkers for the disease and better understand what causes it, and why symptoms vary widely among people who have it.
Seeking boys and men with Duchenne muscular dystrophy (DMD) or Becker Muscular Dystrophy (BMD) to provide samples including blood, plasma, serum, urine, as well as the remainders of tissue samples collected as part of their usual clinical care for a biorepository.
Seeking male participants aged 10-21 years of age who have been diagnosed with Duchenne Muscular Dystrophy (DMD) for participation in an imaging study.
Seeking men and women whose doctor has recommended surgery to relieve pain resulting from damage to a disc in their back being pushed out of place (herniated) for a study of an investigational device to prevent the disc from reherniating.
This study is intended to collect data from medical records on patients who have Duchenne Muscular Dystrophy
Seeking adults with degenerative spondylolisthesis with lumbar spinal stenosis whose doctors have recommended back surgery to address the pressure on your spinal cord or spinal nerves
Seeking men and women with moderate to severe rheumatoid arthritis that has not responded or has stopped responding to biologic or disease-modifying Anti-Rheumatic drugs for a study of an investigational device.
Seeking men and women whose active systemic lupus erythematosus (SLE) is being treated with non-biologic therapy for a study of an investigational drug.
Seeking men and women whose rheumatoid arthritis has not responded to TNF-biologic treatment for a study comparing two different types of treatments (non-TNFi-biologic and tsDMARDs).
Seeking men and women whose broken arms or legs will need to be treated with surgery for a study of what treatment practices best prevent infection.
Seeking adults who have inflammatory arthritis and who are willing to provide data by answering questionnaires, giving a blood sample and donating leftover tissue samples for a study to help researchers better understand inflammatory arthritis.
Seeking people aged 9 and older who have epilepsy with focal seizures that has not responded to treatment for a study of an investigational device
Seeking men and women aged 18 and older for a study of a device to help develop a Magnetic resonance imaging (MRI) technique to improve scans of the brain.
Seeking people aged 6 and older who have Tourette Syndrome and both motor and vocal tics that cause impairment with normal routines for a study of an investigational drug.
Seeking men and women over the age of 65 for a study of an investigational device to screen for cognitive impairment.
Seeking men and women 18 years of age or older to complete surveys to help determine how people decide to participate in Parkinson's disease research
Seeking men and women with Adrenomyeloneuropathy for a gene therapy study to try and correct gene defects so that nerve cells can create proteins needed to prevent damage to spinal cord cells and nerves.
Seeking men and women with multiple sclerosis for a study of how common sleep apnea is and whether sleep apnea affects MS symptoms.
Seeking women and men who have started ocrelizumab treatment for their Multiple Sclerosis (MS) within the past month or people whose MS is being being treated with therapies other than ocrelizumab for a study looking at the incidence of cancer in the future.
This is a registry to collect medical record information from people living with Multiple Sclerosis (MS) to better understand the disease and develop new treatments
Seeking men and women with relapsing multiple sclerosis whose doctors has decided to start treatment with clabridine tablets because other pills were not working well.
Seeking men and women diagnosed with Multiple sclerosis (MS) within the past 2 years for a study of whether ocrelizumab (study drug) can be used for a period of time rather than permanently and still control your early relapsing MS disease activity.
Seeking men and women aged 18-80 who need treatment for an intracranial aneurysm (a bulge in a blood vessel in the brain that could rupture and bleed into the brain) for a study of a device called a coil to prevent rupture.
Seeking men and women who have had a recent stroke or transient ischemic attach (TIA) often called a "mini-stroke" for a study of the benefits of using a continuous positive airway pressure (CPAP) machine while sleeping.
Seeking men and women with early Parkinson's Disease for a study of an investigational drug to slow the development of disease symptoms.
Seeking men and women with atrial fibrillation and a recent brain hemorrhage causing increased risk for stroke for a study of blood thinners to reduce risk of stroke.
Seeking men and women with multiple sclerosis (MS) that hasn't responded to previous treatment for a study of an experimental drug.
Seeking men and women who have a wide-necked, bifurcated saccular intracranial aneurysm that requires endovascular treatment for a study of an investigational device.
Seeking men and women whose doctor has recommended treatment for an acute ischemic stroke for a study collecting blood clots and medical information to better understand how to treat and prevent acute ischemic stroke.
Seeking men and women aged 50 and older who have had bleeding in the brain (brain hemorrhage) for a study comparing continuing or stopping statin drug use treatment on the risk of having another brain hemorrhage.
Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.
Seeking people with Parkinson's disease and healthy volunteers for a study of how speech changes depending on PD symptoms, effects of medication and genetics.
Seeking men and women with Amyotrophic Lateral Sclerosis (ALS) to participate in a research trial to test several different investigational treatments.
Seeking men and women whose multiple sclerosis has remained active despite treatment for a study comparing blood stem cell transplantation to other available treatments for multiple sclerosis.
Seeking men and women aged 18 and older who have been admitted to the hospital intensive care unit following a traumatic brain injury for a study of how care received in the hospital impacts long-term recovery.
This study is enrolling men and women who have had a traumatic brain injury in order to compare outcomes when medical care is delivered based on either monitoring the pressure in the brain or monitoring both the pressure in the brain and the amount of oxygen in the brain.
Seeking men and women who are within the first few hours of experiencing an ischemic stroke (caused by a blood clot blocking blood flow to the brain) for a study comparing medication combinations to reduce the impact of the stroke.
Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.
Seeking men and women aged 22-75 who need treatment for an intracranial aneurysm (a bulge in a blood vessel in the brain that could rupture and bleed into the brain) for a study of a device called a coil to prevent rupture.
Seeking men, women, and children to participate in a trial looking at a combination of drugs for use in treating a type of cancer called rhabdomyosarcoma (RMS).
Seeking people with Mycosis Fungoides for a study to develop a test for Mycosis Fungoides.
Seeking women scheduled for a routine screening mammogram for a study comparing Artificial Intelligence (AI) software to standard guidelines for predicting breast cancer risk.
Seeking men and women who have been referred for follow-up imaging after a positive CT scan screen for lung cancer for a study of a blood test for early detection of lung cancer.
Seeking people aged up to 21 years for a study of decreasing the length of chemotherapy treatment for people with low risk rhabdomyosarcoma and increasing the length of chemotherapy treatment for people with high risk rhabrhabdomyosarcoma.
Seeking men and women with metastatic cancer that has spread to their brain and progressed or grew back after treatment for a study of an investigational immunotherapy drug based on the gene type and source of the original cancer to prevent growth of metastatic tumors in the brain.
Seeking men and women whose meningioma (cancer of the brain covering) has gotten bigger or grew back after treatment for a study of whether cancer drugs targeting tumors based on their genetics is better, the same, or worse than the standard treatment for meningiomas.
Seeking men and women with untreated metastatic anal cancer for a study on whether adding an immune checkpoint inhibitor drug to the usual chemotherapy helps prevent the cancer from getting worse.
Seeking male and female participants under the age of 25, who were diagnosed with Chronic Myeloid Leukemia before the age of 18, to determine if they can stop taking their TKI medication and remain in remission as well as if restarting TKI will re-achieve remission.
Seeking men and women who have been diagnosed since January 1, 2020, with metastatic non-small cell lung cancer and have been or will be treated with immunotherapy, chemotherapy or a combination of the two for a study to develop a tool to help guide treatment decisions.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Seeking men and women who have had a lung nodule detected during imaging for collection of nasal swab and blood samples.
Seeking people aged 30 and younger newly diagnosed with diffuse anaplastic Wilms tumor, a type of cancer that occurs in the kidney, for a study of experimental treatment regimen because no standard treatment regimen currently exists.
Seeking men and women who are current smokers for a study of motivational text messages to help people stop smoking.
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking men and women aged 18 and older whose colon, peritoneal, or rectal cancer will be treated with surgery (resectable) for a study of an investigational drug to make the cancer cells glow under infrared light.
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
Seeking people aged 3 to 25 with newly-diagnosed high-grade glioma whose brain tumor has been genetically tested to show that it does not have the H3, K27M and BRAF mutations for a study of an investigational drug. The study will compare whether adding the investigational drug to radiation and maintenance therapy is better than the usual treatment.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
This study is looking at using different experimental treatment methods for children diagnosed with Acute Myeloid Leukemia (AML) and Down Syndrome (DS) based on how well they respond to their first treatment.
Seeking male and female children ranging from 0-18 months of age diagnosed with non-high risk neuroblastoma.
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking men and women 18 years or older with certain types of lung cancer to help test whether a combination of drugs can help the immune system.
Seeking men and women with a specific form of lung cancer to test if a combination of two specific drugs is beneficial.
Seeking men and women whose high-risk, non-muscle invasive bladder cancer has not spread to the muscle for a study comparing the standard Bacillus Calmette-Guerin (BCG) immunotherapy to an investigational chemotherapy drug combination.
Seeking men and women with colorectal cancer who will undergo colorectal surgery to remove part of their colon or rectum for a study of the healing process
Seeking men and women over 18 years of age who have a specific form of cancer called Follicular Lymphoma to determine if adding a new drug to existing treatments can lead to improvements in individuals where their cancer has come back or did not get better compared to existing treatments alone
Seeking people who have who have already taken endocrine therapy for two to five years for their early-stage ER+/HER2- breast cancer and have a higher-than-average risk for their cancer to return for a study to compare the investigational drug to standard hormone therapy.
Seeking men and women who have a type of cancer that affects the B-cells (a type of white blood cells) in your blood that has not responded to, or who could not tolerate, the standard treatments normally given for this type of cancer for a study of an investigational drug.
Seeking men and women whose multiple myeloma has returned or gotten worse despite treatment for a study comparing investigational drug combinations.
Seeking men and women who have Multiple Myeloma (MM) and will undergo Autologous Stem Cell Transplant (ASCT) as a form of treatment for a study of an investigational drug to help collect blood stem cells.
Seeking men and women whose locally-advanced stage III Non-small Cell Lung Cancer (NSCLC) can not be treated with surgery for a study of adding an investigational drug to the standard chemoradiation therapy.
IRONMAN Registry aims to collect detailed information about the participants in the study at the time of enrollment and to follow their medical care to better understand what treatments work and where there are unmet needs in their treatment.
Seeking men and women aged 18-65 years whose large B-Cell lymphoma has not responded or come back after treatment for a study of an investigational drug combination.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
Seeking men and women over 18 years of age who have been diagnosed with metastatic esophageal carcinoma for a study of two drugs in addition to chemotherapy as compared to the standard of care.
Seeking men and women whose multiple myeloma has returned or has not responded to their most recent treatment for a study adding an investigational drug to the usual treatment.
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking children aged 2.5 to 7 years old suspected to have Autism Spectrum Disorder (ASD) and those who do not for a study of a test to diagnose and assess ASD.
Seeking men aged 18-45 with Fragile X Syndrome for a study of an investigational drug.
Seeking infants admitted to the NICU with an unexplained likely genomic illness for a study of the benefit of genomic testing on their care.
Seeking teens aged 15-18 years old who were enrolled in the ELGAN study of premature infants between April 2002 and August 2004 for a follow-up study of health and developmental progress.
Seeking men and women aged 65 and older for a study of changes in the microbiome in the intestines of seniors when they move into a long-term care facility.
Seeking men and women aged 50 and older who will be transferred to a long-term care facility, have been a resident of a long-term care facility for more than one month, or who live in the community and attend senior center programs for a study of the gut microbiome to better understand risk factors for Clostridium Difficile (an intestinal infection that causes severe diarrhea)
Seeking people whose recurrent Clostridium difficile (C. diff) infection has not responded to standard antibiotic treatments for a study to see if fecal microbiota transplantation is effective for treating C. diff infection.
We are collecting data and biological samples from people with infectious or inflammatory conditions of the bowel such as celiac disease, colitis, and Inflammatory Bowel Disease (IBD) and from people who do not have bowel disease to get a better understanding of these diseases.
Seeking men and women 18 years of age or older who have a diagnosis of ulcerative colitis (UC) for participation in a study looking at an investigational drug and how effective it is.
Seeking men and women with eosinophilic esophagitis (EoE), a chronic allergic inflammatory disease of the esophagus (food pipe) that may cause difficulty swallowing, for a study of the long-term effect of dupilumab on esophageal function and remodeling.
Seeking men and women with non-alcoholic steatohepatitis (NASH) cirrhosis for a study of an investigational drug to reduce the amount of fat and inflammation in the liver.
Seeking men and women over 18 years of age who are having a specific kind of endoscopic procedure with imaging to determine how well a a computer program can analyize these images compared to what your doctor determines.
Seeking men and women with uncomplicated diverticulitis for a study of fecal transplantation as an alternative to surgery to treat diverticulitis.
This research is collecting data on nicotine cravings in patients with chronic pancreatitis who smoke cigarettes.
Seeking people with eyelid motility disorder preventing their eyelids from opening and closing normally for a study of an investigational device.
Seeking people who have experienced vision loss of one half the field of vision on the same side in both eyes (Homonymous Hemianopia) for a study of investigational prism eyeglasses.
Children and adults who either have macular degeneration or are closely related to someone who has macular degeneration are sought for a study of macular degeneration and other related ocular disorders to prevent visual loss and blindness for current and future generations
Seeking adult male and female healthy volunteers for a national research program enrolling one million people across the U.S. to help build one of the most diverse health databases in history.
Seeking male participants aged 12 to less than 18 years of age for a study of an investigational drug and it's safe and effectiveness for participants with Fragile X Syndrome
Seeking boys and girls with Fragile X Syndrome who were born between 2003 and 2017 for a registry to better understand how to manage and treat Fragile X Syndrome.
Seeking men and women who get their care at UMass Memorial for a chronic health condition such as heart disease, diabetes or kidney disease for a study of an investigational device embedded in a toilet seat to remotely monitor cardiac health.
Seeking men and women 18 years and older who have been referred for a procedure called a Coronary angiography to look at blockages in the coronary arteries
Seeking men and women who are experiencing symptoms of a heart attack including chest pain and shortness of breath for a study of the effect of stress on heart function and the development of stress cardiomyopathy.
Stroke survivors aged 50 and over sought for a study to develop and test a wearable sensor to monitor for atrial fibrillation (abnormal heartbeats)
Seeking men and women with vessel disease in the leg (also known as chronic limb-threatening ischemia) for a study of an investigational device to increase blood flow to the lower leg and prevent the need for amputation.
Seeking men and women 18 years of age or older who have been diagnosed with a specific type brain aneurysm for study of the long term safety of an approved device (WEB®) intended to treat this issue.
Seeking men and women 18 to 80 years of age who have been diagnosed with a specific type brain aneurysm for study of an investigational device intended to treat this issue.
Seeking men and women who are experiencing ischemic stroke for a study of an investigational device to remove the blood clot using suction and restore blood flow to the brain.
Seeking men and women with heart failure due to a dilated left ventricle (heart chamber that pumps blood) for a study of an investigational device.
Seeking men and women with a blood clot causing Deep Vein Thrombosis for which their doctor has recommended surgical treatment for a study of an investigational device inserted into the vein using a catheter to remove the clot.
Seeking men and women with peripheral artery disease (PAD) causing pain in the legs when walking or climbing stairs for a study of an investigational dietary supplement combination to improve blood flow.
Seeking men and women experiencing a stroke caused by a blood clot in their brain and whose National Institute of Health Stroke Scale (NIHSS) is 6 or more for a study comparing surgically removing the clot to the standard practice of medical management with drugs and physical therapy.
Volunteers who are at risk for having heart disease, taking aspirin, and will be or have already undergone a cardiac catheterization sought for a study of how the body makes blood clots and its effect on the risk for heart attack and stroke.
Seeking men and women diagnosed with severe aortic valve stenosis for a study of an investigational device to replace the aortic valve.
Seeking men & women 18 years old and over who have a cardiomyopathy (impairment of your heart muscle strength) from coronary artery disease (hardening of the arteries).
Seeking men and women over the age of 18 who have been diagnosed with an aortic aneurysm (bulging of the vein that carries blood to your heart) that because of their anatomy can't be treated using an FDA-approved graft. This study would use endografts that are customized by the doctor to the anatomy of each patient to treat these complex aortic aneurysms.
Seeking adult patients whose doctor has ordered a test called a Cardiac Catheterization to check for and possibly fix blockages in the heart. The doctor performing the cardiac catheterization will decide which patients who volunteer for the study are suitable participants.
Seeking men and women who have been treated for episodes of low blood sugar at the UMass Memorial Diabetes Center of Excellence for a study to see if a smartwatch can sense low blood sugar.
Seeking men and women with type 2 Diabetes Mellitus to participate in an expert panel for a study to develop and test a technology to help people manage their diabetes.
Seeking blood samples from healthy volunteers and volunteers who have various autoimmune diseases, like type 1 diabetes
Seeking participants between the ages of 6 and 65 to participate in a study about appetite and weight related to a specific gene variation and whether a specific drug can control this.
Seeking healthy men and women volunteers aged 12-55 for a study of an investigational vaccine against Epstein Barr Virus which is the main cause of mononucleosis.
We invite people who are Latinx and/or Black and have been vaccinated against COVID-19 to tell us how COVID-19 has affected you and your family and your experience with getting the COVID-19 Vaccines and the first booster.
Seeking babies aged 12 weeks to less than 6 months old for a study of a COVID vaccine.
Seeking parents of kids aged 5-17 who receive their care at UMass Memorial for a research survey about their intentions on having their child vaccinated against COVID-19.
Seeking men and women aged 65 and older who have been hospitalized for what may be pneumonia for a study of the effectiveness of vaccines against pnuemonia.
Seeking men and women aged 18 and older who get their care at UMass Memorial clinics to participate in a focus group on outreach materials for COVID-19 vaccination.
Seeking children who have been diagnosed with influenza in the past 7 days and healthy children willing to donate a blood sample for a study of how influenza affects blood cells of children.
Seeking men and women hospitalized for a COVID-19 infection for a study of whether adding an investigational drug to the usual treatment improves recovery.
Seeking men and women with an Respiratory Syncytial Virus (RSV) Infection and who are at risk of progression to severe illness for a study of an investigational drug
Seeking hospitalized men and women who are on supplemental oxygen because of a viral lung infection for a study of an investigational drug added to the usual treatment
Seeking people aged 21 and younger who have lyme disease and likely have meningitis that has not yet been treated. To participate in a study comparing two different antibiotic treatments
Seeking healthy adults and adults who have been suffering influenza-like illness for no more than 14 days for a study of how the flu or flu-like infections affect their blood cells.
Seeking men and women with Chronic Obstructive Pulmonary Disease (COPD) for a study of an mobile digital device app to provide in-home support to manage COPD.
Seeking people with Cystic Fibrosis aged 12 and older for a study of blood, sputum, and/or leftover fluid collected during your bronchoscopy to look at how your body responds to infection or inflammation.
Seeking intubated (tube placed in someone's throat to help them breathe) people for a study of an investigational device to improve their communication with caregivers.
Seeking men and women with either normal airways or airways that have been difficult to manage while under anesthesia for a study of a voice test might reliably predict people whose airways may be difficult to manage during an operation.
Preterm Infants diagnosed with pauses in breathing (apnea of prematurity) and treated for intermittent hypoxia using caffeine sought for study of longer-term caffeine treatment
This is an observational study of patients with cystic fibrosis. Any patient diagnosed with cystic fibrosis can participate.
Seeking men and women with Active Systemic Lupus Erythematosus (SLE) to undergo testing of CABA-201, an Autologous CD19-specific Chimeric Antigen Receptor T cells,
We are collecting blood samples from healthy controls and Systemic Lupus Erythematosus (SLE) patient samples to learn more about potential molecules that are responsible for the development of Lupus.
Seeking men and women with opioid use and mental health disorders for a study of different combinations of treatments.
Seeking men and women to be interviewed about their health and medication use for a study about long-term use of medications.
Seeking men and women initiating treatment for opioid use disorder with extended-release bupenorphrine for a study of an investigational wearable sensor and mobile app to monitor cravings
Seeking transgender patients who receive either hormone replacement therapy (HRT) alone or gender confirmation top-surgery in addition to HRT for a study of the impact of treatment.
Seeking veterans with post-traumatic stress disorder (PTSD) or PTSD symptoms for a study of an intervention to see if observing and caring for injured or orphaned wildlife at a wildlife rehabilitation center helps to reduce PTSD symptoms.
Seeking deaf adults and ASL users who is experiencing problems with alcohol use and trauma for an experimental intervention that we hope will reduce symptoms of addiction.
Study comparing two interventions to reduce suicidal behaviors and thoughts for people admitted to the emergency department or psychiatric unit of the hospital who recently attempted suicide or had suicidal thoughts
Seeking men and women whose depression has not been fully helped by other treatments, also known as treatment resistant depression for a study of an investigational drug that contains a man-made form of psilocybin (the active ingredient in psychedelic mushrooms known as "magic mushrooms" or "shrooms")
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.
Seeking women 18 years and older who are mothers to infants who had previously been hospitalized in the NICU at UMass Memorial Health within the last 6 months for a study about skin-to-skin contact (called "Kangaroo Care")
Seeking boys aged 4-9 with Duchenne Muscular Dystrophy for a study of an investigational drug to prevent muscle damage.
Seeking women who are expectant or new mothers to participate in recorded interview sessions discussing experiences and opinions on weight and stigmas and a proposed intervention.
Seeking women in the Worcester area who are pregnant or have recently given birth for a study of a breastfeeding support app.
This study is collecting tissue and information from pregnant women who are having cesarean births to gain a better understanding of how the uterus functions.
Seeking pregnant women with chronic hypertension, gestational hypertension or a history of hypertensive disorders of pregnancy for a brief survey of their experiences and approaches to healthy eating.
Pregnant women with either normal or high blood pressure sought for a study of the effects of high blood pressure during pregnancy. The study will assess whether future cardiovascular disease or serious pregnancy complications like preeclampsia can be better detected & prevented.
Pregnant women who are in their late 2nd to 3rd trimester who have high blood pressure are sought for a study to develop a screening test for preeclampsia in pregnant women. We will collect samples of your blood, urine, and saliva to see if we can detect levels of a protein that would help accurately predict who will get preeclampsia.
Seeking people who either have vitiligo or are closely related to someone who has vitiligo for a study of genetic factors that may impact the start or progression of vitiligo
Seeking healthy adult volunteers or adults who has had skin allergy patch testing in the past for a study of how anti-inflammatory therapies work in inflamed skin.
Seeking males and females with Vitiligo to learn more about whether they are more or less likely to have increased complications related to vision and hearing.
We are studying how skin diseases occur in the skin, including how immune cells choose to initiate disease as well as what causes them to enter the skin.
Seeking men, women, and children, 6 years and older who have a skin condition to provide data and specimens for laboratory studies.
Seeking men and women over 18 years of age who have been diagnosed with hidradenitis suppurativa (HS) for participation in a study looking utilizing Botox
Seeking people aged 6 and older with wounds caused by recessive dystrophic epidermolysis bullosa (RDEB) for a study of an investigational gene therapy.
Seeking people who need immediate care for frostbite for a study of an experimental method to rewarm frostbitten skin.
Seeking children under 18 years of age and healthy volunteers from 6 to 18 to study the skin immune system.
Seeking men and women with or without an inflammatory skin disease ( such as cutaneous lupus erythematosus, dermatomyositis, atopic dermatitis, alopecia areata, scleroderma, eczema, psoriasis, vitilago, or drug hypersensitivity) for a study to learn more about skin diseases and their response to light.
Seeking men and women who take blood thinning medication and who will have Mohs surgery to remove skin cancer cells for a study of an investigational drug to reduce bleeding during surgery.
Seeking men and women 18 years of age or older who have had a stroke caused by bleeding in their brain to help determine is a new drug called recombinant factor VIIa (rFVIIa) can improve outcomes compared to a placebo when added to the standard care provided after a stroke.
Men and women over 18 years old who have a diagnosis of acute ischemic stroke (AIS) and have been given intravenous thrombolysis (IVT) treatment.
Seeking men and women aged 18 and older for a study of sensors worn on or applied to the skin to measure pain.
Seeking men and women who will be admitted to the minimally invasive surgery service at UMass Memorial for a study of how walking after surgery helps with healing.
Seeking children who have been referred for outpatient ear surgery for a study comparing two drugs for managing pain and preventing emergence delirium when they are waking up from anesthesia following surgery.
Seeking men and women whose doctor has scheduled them for surgery to repair a colovesical fistula (CVF) for a study of the timing of foley catheter removal following surgery.
Seeking men and women aged 18-85 whose degenerative disc disease or spondylolisthesis requires spinal fusion surgery with bone grafting for a study of a synthetic bone graft.
Seeking men and women who will undergo a total knee replacement (arthroplasty) surgery at UMass Memorial for a study of an investigational device to monitor post-surgery recovery
Seeking men and women aged 65 or older who have been discharged from the hospital within the past month for a survey of their health and use of healthcare following their discharge from the hospital.
Seeking men and women who will be undergoing surgery or being cared for in an intensive care unit and who will require an intra-arterial catheter for a study of a investigational device similar to a wristwatch to continuously monitor blood pressure.
Seeking men and women, 18-80 years of age, who have experienced blunt head trauma with loss of consciousness for study of a new device to detect traumatic brain injury through blood testing.
Seeking men and women willing to use continuous glucose monitors and working with community health workers and clinical pharmacist to see if these can improve blood sugar control
Seeking adult men and women who have a wound that their medical provider has recommended be treated with a surgical procedure.
Seeking Men and Women over 18 years of age with moderately to severely active ulcerative colitis for participation in a study of an investigational product called Efavaleukin Alfa