Conquering Diseases

A Study Of Treatments For Pediatric And Adult Patients With Germ Cell Tumors


We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.


Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of standard risk tumor cells. This study will randomly assign standard risk participants to be treated with either cisplatin or carboplatin to compare them to find out which is better.

What we're hoping for

We hope to find an effective treatment that reduces the risk of long term side effects from chemotherapy for children and adults with germ cell tumors.

Additional Information Identifier: NCT03067181

 Principal Investigator

Stefanie  Lowas, MD

UMass Chan Medical School

 Study Contact

Pediatrics Hem-Oncology  Research Center



UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655