Conquering Diseases

201 Studies found

Blood Disorders

Blood Disorders

Blood Disorders

Blood Disorders

Blood Disorders

Bone Joint and Muscle Diseases

Limiflex Control Site Study

Seeking adults with degenerative spondylolisthesis with lumbar spinal stenosis whose doctors have recommended back surgery to address the pressure on your spinal cord or spinal nerves

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Michael Stauff

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Gender

Male/Female

Age

6 months +

Compensation

None

Image of Terence Flotte

Bone Joint and Muscle Diseases

Study Of Biomarkers In Facioscapulohumeral Muscular Dystrophy (Fshd)

Seeking adults aged 18 and older who either have Facioscapulohumeral Muscular Dystrophy (FSHD) or are healthy volunteers for a study to identify genetic biomarkers for the disease and better understand what causes it, and why symptoms vary widely among people who have it.

Healthy Volunteers Wanted.

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Portable Hyperspectral Imaging (Hsi) Study

Seeking Men and Women 18 years or older who are having an operation that will require the creation of a flap of tissue (where a piece of skin/muscle is taken from one part of the body and moved to another part), or because you have a traumatic degloving injury (an injury where the skin is torn away from the tissue underneath).

Bone Joint and Muscle Diseases

Gender

Male/Female

Age

18 or older

Compensation

Offered

Image of Jonathan Kay

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Study Of Inflammatory Arthritis

Seeking adults who have inflammatory arthritis and who are willing to provide data by answering questionnaires, giving a blood sample and donating leftover tissue samples for a study to help researchers better understand inflammatory arthritis.

Bone Joint and Muscle Diseases

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Eric Swart

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Bone Joint and Muscle Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Study Of Stress Reduction In Multiple Sclerosis

Seeking men and women with Multiple Sclerosis for a study of the role of stress in multiple sclerosis and whether an 8-week mindfulness-based stress reduction (MBSR) program effects your sense of well-being, stress level, and how it may change your brain.

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Gender

Male/Female

Age

18-80 years

Compensation

None

Image of David Rex

Brain and Spinal Cord Diseases

Nano Registry

Seeking Men and Women 18-90 years old who have a small ruptured or un-ruptured aneurysm in the head.

Brain and Spinal Cord Diseases

Experimental Treatment For Strokes

This study is looking at an experimental treatment for patients diagnosed with a stroke caused by a blockage in the blood vessels within the brain.

Brain and Spinal Cord Diseases

Impact Of Fever Prevention In Brain Injured Patients

Seeking patients who have suffered a brain injury like ischemic stroke, intracerebral hemorrhage or subarachnoid hemorrhage for a study of an investigational medical device to prevent fever while in the hospital

Brain and Spinal Cord Diseases

Traditional Versus Early Therapy For Multiple Sclerosis (Treat-Ms) Trial

Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Study Of Drug Therapy To Prevent Stroke From Happening Again

Seeking Ischemic (caused by reduced blood flow by narrowed or blocked arteries) stroke survivors aged 45 and older for a study of an investigational therapy using anticoagulant drugs (aspirin or apixiaban) for the prevention of another stroke

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Multi-Arm Optimization Of Stroke Thrombolysis (Most)

Seeking men and women who are within the first few hours of experiencing an ischemic stroke (caused by a blood clot blocking blood flow to the brain) for a study comparing medication combinations to reduce the impact of the stroke.

Brain and Spinal Cord Diseases

A Study Comparing Two Ways Of Treating Patients With Brain Injury

This study is enrolling men and women who have had a traumatic brain injury in order to compare outcomes when medical care is delivered based on either monitoring the pressure in the brain or monitoring both the pressure in the brain and the amount of oxygen in the brain.

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Gender

Male/Female

Age

Adult

Compensation

None

Image of Kara Smith

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Registry To Study Genetic Origins Of Multiple Sclerosis

Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.

Healthy Volunteers Wanted.

Brain and Spinal Cord Diseases

Gender

Male/Female

Age

50 and older

Compensation

None

Image of Majaz Moonis

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Brain and Spinal Cord Diseases

Cancer Research

Gender

Male/Female

Age

Up to 40 Years

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

0 - 18 months

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

3 and under

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

All

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

0-25 years

Compensation

None

Image of Stefanie Lowas

Cancer Research

Study Of Kidney Tumors In Younger Patients

Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.

Gender

Male/Female

Age

0-30 years

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

11-24 years

Compensation

None

Image of Stefanie Lowas

Cancer Research

Cancer Research

Study Of An Investigational Drug For High-Grade Glioma In Children And Young Adults

Seeking people aged 3 to 25 with newly-diagnosed high-grade glioma whose brain tumor has been genetically tested to show that it does not have the H3, K27M and BRAF mutations for a study of an investigational drug. The study will compare whether adding the investigational drug to radiation and maintenance therapy is better than the usual treatment.

Gender

Male/Female

Age

3- 25

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

All

Compensation

None

Image of Stefanie Lowas

Cancer Research

Study To Improve Lung Cancer Screening

Seeking men and women who are or have been smokers and are at greater risk for lung cancer for a study to improve lung cancer screening

Healthy Volunteers Wanted.

Cancer Research

Gender

Male/Female

Age

1-25

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

31 or younger

Compensation

None

Image of Stefanie Lowas

Cancer Research

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Jonathan Gerber

Cancer Research

Cancer Research

A Study Of Cancer Tumors (Avatar)

This study is collecting tumor tissue, body fluids and blood samples from patients undergoing biopsies or surgery to gain a better understanding of different cancers.

Cancer Research

Cancer Research

Rectal Cancer Surgery Research

Seeking adults with rectal cancer requiring surgery for a study comparing an investigational surgery to the standard surgery technique

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Study Of An Experimental Drug For Melanoma Skin Cancer

Seeking men and women who have been diagnosed with melanoma skin cancer and will have surgery to remove it for a study of whether starting the experimental drug before surgery is better or worse than starting the drug after surgery.

Cancer Research

Cancer Research

Cancer Research

Study Of Liquid Biopsy Cancer Screening For Esophageal Cancer

Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.

Cancer Research

Cancer Research

Cancer Research

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Madhavi Toke

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Nahida Islam

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Cancer Research

Gender

Male/Female

Age

70 and older

Compensation

None

Image of Venu Bathini

Cancer Research

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Giles Whalen

Cancer Research

Developmental Disorder

Gender

Male/Female

Age

12-16

Compensation

None

Image of Carol Curtin

Developmental Disorder

Gender

Male/Female

Age

5-17 years

Compensation

Offered

Image of Jean Frazier

Developmental Disorder

Developmental Disorder

Digestive and Liver Diseases

Digestive and Liver Diseases

Gender

Male/Female

Age

All

Compensation

None

Image of Krunal Patel

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

None

Image of Deepika Devuni

Digestive and Liver Diseases

Gender

Male/Female

Age

65 and older

Compensation

Offered

Image of John Haran

Digestive and Liver Diseases

Digestive and Liver Diseases

Laser Fistula Study

Seeking Men and Women 18-65 years old who have a fistula-in-ano that needs treatment.

Digestive and Liver Diseases

Reverse: A Study Of An Investigational Drug For Compensated Cirrhosis Due To Nonalcoholic Steatohepatitis (Nash)

Nonalcoholic Steatohepatitis (NASH) results when fat accumulates in the liver and causes inflammation and scarring called fibrosis. Fibrosis can lead to cirrhosis which impairs liver function. Ocaliva (OCA) is an FDA approved drug for treating another type of liver disease. This study will test if Ocaliva (OCA) is safe and effective in treating cirrhosis of the liver caused by advanced NASH.

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Digestive and Liver Diseases

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

None

Image of David Cave

Digestive and Liver Diseases

Alcoholic Hepatitis Network Observational Study

Seeking healthy volunteers who either drink less than 1 drink per week on average or at least 3 drinks per day for a study collecting biological samples (blood, urine, and stool) and health information to better understand alcoholic hepatitis.

Healthy Volunteers Wanted.

Digestive and Liver Diseases

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Justin Maykel

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Eye and Vision Diseases

Macular Degeneration And Other Related Ocular Disorders

Children and adults who either have macular degeneration or are closely related to someone who has macular degeneration are sought for a study of macular degeneration and other related ocular disorders to prevent visual loss and blindness for current and future generations

Healthy Volunteers Wanted.

Gender

Male/Female

Age

7 and older

Compensation

None

Image of Johanna Seddon

Eye and Vision Diseases

Heart and Blood Vessel Diseases

Gender

Male/Female

Age

Adult

Compensation

None

Image of Jeffrey Shih

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Gender

Male/Female

Age

70 or older

Compensation

Offered

Image of Diane McKee

Heart and Blood Vessel Diseases

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Jinying Chen

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Aortic Aneurysm Repair Using Endovascular Surgery And Custom Made Devices

Seeking men and women over the age of 18 who have been diagnosed with an aortic aneurysm (bulging of the vein that carries blood to your heart) that because of their anatomy can't be treated using an FDA-approved graft. This study would use endografts that are customized by the doctor to the anatomy of each patient to treat these complex aortic aneurysms.

Heart and Blood Vessel Diseases

Mindfulness Heart Study

Seeking men & women 18 years old and over who have a cardiomyopathy (impairment of your heart muscle strength) from coronary artery disease (hardening of the arteries).

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Study Of An Investigational Drug To Reduce Brain Swelling Caused By A Stoke

Seeking men and women who are within 10 hours from the time they started to have stroke symptoms for a study of how well people who get the investigational drug in additional to the usual treatment recover compared to people who get a medicine without any active drug (placebo) in addition to the usual treatment.

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Study Of A Device Used To Treat Ischemic Stroke

Seeking men and women who will be undergoing a medical procedure to remove a blood clot or blockage from an artery that is blocking blood flow to the brain (ischemic stroke) for a study of the technical use and safety of a device used during the procedure.

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Heart and Blood Vessel Diseases

Hormonal Diseases and Diabetes

Gender

Male/Female

Age

18 and over

Compensation

Offered

Image of Dale Greiner

Hormonal Diseases and Diabetes

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Silvia Corvera

Hormonal Diseases and Diabetes

Infectious Diseases

Gender

Male/Female

Age

Child

Compensation

Offered

Image of Laura Gibson

Infectious Diseases

Study Of How The Flu Affects Blood Cells

Seeking healthy adults and adults who have been suffering influenza-like illness for no more than 14 days for a study of how the flu or flu-like infections affect their blood cells.

Healthy Volunteers Wanted.

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

2-10 years old

Compensation

Offered

Image of Milka Koupenova

Infectious Diseases

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Robert Finberg

Infectious Diseases

Covid-19 Plasma Registry

Seeking people, local to central Massachusetts, who are fully recovered from the new coronavirus to sign up to donate plasma to help current COVID-19 patients.

Infectious Diseases

Infectious Diseases

Infectious Diseases

Gender

Male/Female

Age

12 and older

Compensation

Offered

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

Adult

Compensation

None

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

18 and older

Compensation

None

Image of Robert Finberg

Infectious Diseases

Gender

Male/Female

Age

1 and older

Compensation

None

Image of Ann Moormann

Infectious Diseases

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Robert Finberg

Infectious Diseases

Study Of Immune Responses To Covid-19

Seeking people previously diagnosed with COVID-19 willing to donate a blood sample for a study of immune responses to the COVID-19 virus.

Healthy Volunteers Wanted.

Gender

Male/Female

Age

All

Compensation

Offered

Image of Robert Finberg

Infectious Diseases

Biorepository For Covid-19 Samples

Seeking men and women willing to provide additional nasal, saliva and blood samples when being tested for COVID-19 for a biorepository to support development of tests for COVID-19 and studies of how COVID-19 causes disease in people.

Healthy Volunteers Wanted.

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Laura Gibson

Infectious Diseases

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Laura Gibson

Infectious Diseases

Infectious Diseases

Lung Diseases and Breathing

Study To Improve Communication With Patients On Ventilators

Seeking men and women with either normal airways or airways that have been difficult to manage while under anesthesia for a study of a voice test might reliably predict people whose airways may be difficult to manage during an operation.

Gender

Male/Female

Age

Adult

Compensation

None

Image of Jens Walz

Lung Diseases and Breathing

Gender

Male/Female

Age

Adult

Compensation

None

Image of Jens Walz

Lung Diseases and Breathing

Gender

Male/Female

Age

12 and older

Compensation

Offered

Image of Stuart Levitz

Lung Diseases and Breathing

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of Rajani Sadasivam

Lung Diseases and Breathing

Gender

Male/Female

Age

All

Compensation

None

Image of Ted Kremer

Lung Diseases and Breathing

Lung Diseases and Breathing

Mental Health

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Xiaoduo Fan

Mental Health

Study Of An Investigational Drug For Schizophrenia

Seeking men and women who have been diagnosed with schizophrenia or schizoaffective disorder for a study of an investigational drug for negative symptoms, which are thoughts, feelings, or behaviors normally present that are absent or diminished in people with schizophrenia or schizoaffective disorder.

Gender

Male/Female

Age

18-55

Compensation

None

Image of Xiaoduo Fan

Mental Health

Mental Health

Mental Health

Mental Health

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Donna Perry

Mental Health

Gender

Male/Female

Age

18-75

Compensation

Offered

Image of John Haran

Mental Health

Mental Health

Reproductive and Women Health

Reproductive and Women Health

Study To Develop A Screening Test For Preeclampsia In Pregnant Women

Pregnant women who are in their late 2nd to 3rd trimester who have high blood pressure are sought for a study to develop a screening test for preeclampsia in pregnant women. We will collect samples of your blood, urine, and saliva to see if we can detect levels of a protein that would help accurately predict who will get preeclampsia.

Reproductive and Women Health

Study Of The Effects Of High Blood Pressure During Pregnancy

Pregnant women with either normal or high blood pressure sought for a study of the effects of high blood pressure during pregnancy. The study will assess whether future cardiovascular disease or serious pregnancy complications like preeclampsia can be better detected & prevented.

Healthy Volunteers Wanted.

Reproductive and Women Health

Skin and Hair Diseases

Study Involving Clinical Patch Testing Of Skin

Looking for adult volunteers 18 years of age or older with no history of any chronic skin diseases for a research study using clinical patch testing to see their skin’s response to chemical allergens.

Healthy Volunteers Wanted.

Gender

Male/Female

Age

18 and older

Compensation

Offered

Image of John Harris

Skin and Hair Diseases

Gender

Male/Female

Age

6yrs-Adults

Compensation

Offered

Image of John Harris

Skin and Hair Diseases

Skin and Hair Diseases

Study Of Skin Diseases Related To Your Immune System

Seeking people of all ages to participate in an observational study of immune-mediated skin diseases like Atopic Dermatitis, Psoriasis, Alopecia, Vitiligo, Hidradenitis Suppurativa and others. In this type of study we look at your medical history, but do not change the way you are being treated by your doctor.

Skin and Hair Diseases

Skin and Hair Diseases

Skin and Hair Diseases

Study Of A Skin Biopsy Sampling Technique

Seeking men and women with a skin condition called atopic dermatitis, which is a more severe type of eczema, for a study of a skin biopsy sampling technique called microsampling.

Skin and Hair Diseases

Skin and Hair Diseases

Study Of Ultraviolet Light On Inflammatory Or Autoimmune Skin Diseases

Seeking men and women with or without an inflammatory skin disease ( such as cutaneous lupus erythematosus, dermatomyositis, atopic dermatitis, alopecia areata, scleroderma, eczema, psoriasis, vitilago, or drug hypersensitivity) for a study to learn more about skin diseases and their response to light.

Healthy Volunteers Wanted.

Surgery

Gender

Male/Female

Age

Adult

Compensation

None

Image of Jens Walz

Surgery

Gender

Male/Female

Age

40-80

Compensation

None

Image of Eman Nada

Surgery

Surgery

Study Of A Investigational Device To Monitor Blood Pressure

Seeking men and women who will be undergoing surgery or being cared for in an intensive care unit and who will require an intra-arterial catheter for a study of a investigational device similar to a wristwatch to continuously monitor blood pressure.

Surgery