Seeking adult males and females who have recently been diagnosed with severe alcoholic hepatitis (AH) for a study to determine how well two drugs work in treating AH compared to the current standard treatment.
220 Studies found
A Study Of An Investigational Device In The Management Of Patients With A Specific Type Of Atrial Fibrillation (Afib)
Seeking men and women 18 years of age or older for study of a investigational device as an alternative to the current standard of care for atrial fibrillation (AFib).
Seeking Men aged 13 to 40 years of age with Fragile X Syndrome for study of an investigational drug alone and/ or in combination with other drugs.
This is a registry of Pyruvate Kinase patients to study how the disease affects different people and how it is treated around the world.
Adult male and female U.S. recipients of allogeneic or autologous HSC transplants or cellular therapies are eligible to participate in the NMDP Research Sample Repository.
Men and women over 16 years old undergoing transplantation with unlicensed CBUs (cord blood units) will be enrolled. Cord blood units not meeting FDA requirements or not yet approved by the FDA may be used for transplant if the transplant is done as part of a study.
Seeking men & women over 18 years old who have a blood disorder or malignancy to investigate normal and abnormal cell growth.
Seeking people with a bleeding disorder such as Hemophilia or Von Willebrand Disease for a registry to collect health data to address the needs and challenges of people living with bleeding disorders.
Seeking adults with degenerative spondylolisthesis with lumbar spinal stenosis whose doctors have recommended back surgery to address the pressure on your spinal cord or spinal nerves
Study Of An Investigational Implant To Prevent The Discs Between Backbone Vertebrae From Being Pushed Out (Herniating)
Seeking men and women whose doctor has recommended surgery to relieve pain resulting from damage to a disc in their back being pushed out of place (herniated) for a study of an investigational device to prevent the disc from reherniating.
Seeking adults aged 18 and older who either have Facioscapulohumeral Muscular Dystrophy (FSHD) or are healthy volunteers for a study to identify genetic biomarkers for the disease and better understand what causes it, and why symptoms vary widely among people who have it.
Seeking men and women aged 18-65 with Facioscapulohumeral Muscular Dystrophy (FSHD) for a study of an investigational drug to reduce the presence of DUX4 to prevent muscle cells from dying.
Seeking Men and Women 18 years or older who are having an operation that will require the creation of a flap of tissue (where a piece of skin/muscle is taken from one part of the body and moved to another part), or because you have a traumatic degloving injury (an injury where the skin is torn away from the tissue underneath).
This study is intended to collect data from medical records on patients who have Duchenne Muscular Dystrophy
Seeking adults who have inflammatory arthritis and who are willing to provide data by answering questionnaires, giving a blood sample and donating leftover tissue samples for a study to help researchers better understand inflammatory arthritis.
Seeking men and women whose broken arms or legs will need to be treated with surgery for a study of what treatment practices best prevent infection.
Seeking male participants aged 10-21 years of age who have been diagnosed with Duchenne Muscular Dystrophy (DMD) for participation in an imaging study.
Seeking boys and men with Duchenne muscular dystrophy (DMD) or Becker Muscular Dystrophy (BMD) to provide samples including blood, plasma, serum, urine, as well as the remainders of tissue samples collected as part of their usual clinical care for a biorepository.
Seeking boys aged 7 to 21 with Duchenne Muscular Dystrophy with an out-of-frame deletion mutation of the DMD gene amenable to exon 51-skipping treatment for a study of the highest tolerated dose of an investigational drug and if it increases dystrophin levels.
Seeking boys and men aged 12-50 with Becker Muscular Dystrophy for a study of the safety and effectiveness of an investigational drug to prevent muscle weakness.
This is a registry to collect medical record information from people living with Multiple Sclerosis (MS) to better understand the disease and develop new treatments
Seeking men and women with Multiple Sclerosis for a study of the role of stress in multiple sclerosis and whether an 8-week mindfulness-based stress reduction (MBSR) program effects your sense of well-being, stress level, and how it may change your brain.
This study is looking at an experimental treatment for patients diagnosed with a stroke caused by a blockage in the blood vessels within the brain.
Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.
Seeking men and women with a brain aneurysm treated with a medical device called a Flow Diverter to slow the flow of blood into the aneurysm to see how well a software helps a doctor predict if the aneurysm will get smaller and blood flow becomes fully blocked over a year.
Seeking Ischemic (caused by reduced blood flow by narrowed or blocked arteries) stroke survivors aged 45 and older for a study of an investigational therapy using anticoagulant drugs (aspirin or apixiaban) for the prevention of another stroke
Seeking men and women who are within the first few hours of experiencing an ischemic stroke (caused by a blood clot blocking blood flow to the brain) for a study comparing medication combinations to reduce the impact of the stroke.
This study is enrolling men and women who have had a traumatic brain injury in order to compare outcomes when medical care is delivered based on either monitoring the pressure in the brain or monitoring both the pressure in the brain and the amount of oxygen in the brain.
Seeking men and women whose multiple sclerosis has not responded well to previous treatment and whose doctor has decided to start treatment with cladribine tablets and stop treatment with an injectable drug.
Seeking men and women with relapsing multiple sclerosis whose doctors has decided to start treatment with clabridine tablets because other pills were not working well.
Seeking volunteers who will have their brain aneurysm treated using a coil to prevent it from bursting for a study of the long term performance of the coil.
Seeking women and men who have started ocrelizumab treatment for their Multiple Sclerosis (MS) within the past month or people whose MS is being being treated with therapies other than ocrelizumab for a study looking at the incidence of cancer in the future.
Study Of The Effects Of Hospital Interventions Just After A Traumatic Brain Injury Affects Long-Term Outcome
Seeking men and women aged 18 and older who have been admitted to the hospital intensive care unit following a traumatic brain injury for a study of how care received in the hospital impacts long-term recovery.
Seeking men and women aged 18 and older diagnosed with a cerebrovascular saccular aneurysm (also known as a berry aneurysm) in their head for a study of an investigational MRI imaging technique.
Study Of An Investigational Stem Cell Transplant For Treatment Resistant Relapsing Multiple Sclerosis
Seeking men and women whose multiple sclerosis has remained active despite treatment for a study comparing blood stem cell transplantation to other available treatments for multiple sclerosis.
Seeking men and women aged between 18 and 80 for a study of how the brain works when making decisions when the answer is uncertain.
Study Of Multiple Investigational Drugs To Prevent Progression Of Amyotrophic Lateral Sclerosis (Als)
Seeking men and women with Amyotrophic Lateral Sclerosis (ALS) to participate in a research trial to test several different investigational treatments.
Seeking men and women with multiple sclerosis for a study of how common sleep apnea is and whether sleep apnea affects MS symptoms.
Seeking people with Parkinson's disease and healthy volunteers for a study of how speech changes depending on PD symptoms, effects of medication and genetics.
Seeking men and women who are participating in the ARCADIA stroke prevention trial for a study of the effect of the study drugs Apixaban and Aspirin on the occurrence of silent strokes and memory loss.
Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.
Seeking men and women aged 50 and older who have had bleeding in the brain (brain hemorrhage) for a study comparing continuing or stopping statin drug use treatment on the risk of having another brain hemorrhage.
Seeking men and women whose brain aneurysm is at risk of rupture if left untreated for a study of an investigational device for unruptured, wide-neck intracranial aneurysms located on their internal carotid artery or its branches.
Seeking men and women whose doctor has recommended treatment for an acute ischemic stroke for a study collecting blood clots and medical information to better understand how to treat and prevent acute ischemic stroke.
Seeking men and women with relapsing multiple sclerosis for a study of how effective and safe an investigational drug is compared to the usual treatment.
Seeking men and women aged 18-60 for a study of an investigational drug for non-relapsing secondary progressive multiple sclerosis.
Seeking men and women aged 18-55 for a study of an investigational drug for primary progressive multiple sclerosis.
Seeking men and women 18 years of age or older with relapsing multiple sclerosis (RMS) for participation in a study comparing an investigational drug called fenebrutinib to a drug called teriflunomidie.
Seeking men and women 18 years of age or older with primary progressive multiple sclerosis for participation in a study of an investigational drug called Ocrelizumab
Seeking men and women within 24 months of diagnosis with Amyotrophic Lateral Sclerosis (ALS) for a study of an investigational drug.
Seeking adult men and women with multiple sclerosis for a study of an investigational drug that has not yet been tested in people.
Seeking men and women who have a wide-necked, bifurcated saccular intracranial aneurysm that requires endovascular treatment for a study of an investigational device.
Seeking men and women who have had Comaneci device used for the treatment of intracranial aneurysms to collect additional safety and efficacy data.
Seeking adult men and women with HER2 positive breast cancer who have already received treatment to determine if a combination of different drugs is better than the usual treatment alone in preventing this cancer from returning.
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking male and female children ranging from 0-18 months of age diagnosed with non-high risk neuroblastoma.
This study is looking at using different experimental treatment methods for children diagnosed with Acute Myeloid Leukemia (AML) and Down Syndrome (DS) based on how well they respond to their first treatment.
This study is for patients who may have neuroblastoma, a tumor of nerve cells typically found in the stomach, chest or neck of young children. This is a data and sample collection study to help us better understand this disease.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Volunteers who are participating in the NMTRC014 research study for treatment of neuroblastoma survivors who are in remission are sought for a research study of how the study drug is absorbed into the the body.
Seeking people aged 3 to 25 with newly-diagnosed high-grade glioma whose brain tumor has been genetically tested to show that it does not have the H3, K27M and BRAF mutations for a study of an investigational drug. The study will compare whether adding the investigational drug to radiation and maintenance therapy is better than the usual treatment.
Study Of An Investigational Drug For Relapsed Or Refractory Cd22+ B-Acute Lymphoblastic Leukemia (B All)
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
Seeking men and women who are or have been smokers and are at greater risk for lung cancer for a study to improve lung cancer screening
Study Of Chemotherapy For Children And Young Adults With High-Risk B-Cell Acute Lymphoblastic Leukemia (B-All)
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Seeking men and women who are current smokers for a study of motivational text messages to help people stop smoking.
Seeking adults who underwent lung cancer screening within the past three years to complete a survey and interview about this process in order to develop a telehealth intervention and improve adherence to screening follow-up.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Study Of An Investigational Drug For Advanced Relapsed, Refractory, Or Resistant Hematological (Blood) Cancer
Seeking men and women with advanced relapsed, refractory, or resistant hematological (blood) cancer with an IDH mutation that has not responded or stopped responding to prior treatment for participation in a study of an investigational drug.
Seeking men and women with Chronic Myeloid Leukemia diagnosed within the last 3 months for a study of the effectiveness of an investigational drug compared to a Tyrosine Kinase Inhibitor (TKI) drug.
Seeking adult men & women whose tumor cells have a change in a gene called ALK that causes the cells to grow and spread.
This study is collecting tumor tissue, body fluids and blood samples from patients undergoing biopsies or surgery to gain a better understanding of different cancers.
This study is looking to compare different surgical options for treating patients with rectal cancer.
Seeking adults with rectal cancer requiring surgery for a study comparing an investigational surgery to the standard surgery technique
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Study Of Immunotherapy Alone Or In Combination With Chemotherapy For Advanced Nonsquamous Non-Small Cell Lung Cancer
Non-squamous non-small cell lung cancer patients whose cancer has been tested to be PD-L1 positive (a kind of tumor marker) sought for study comparing two usual approaches to treatment.
Seeking men and women aged 18 and older whose colon, peritoneal, or rectal cancer will be treated with surgery (resectable) for a study of an investigational drug to make the cancer cells glow under infrared light.
Men and women with advanced HPV throat cancer sought for a study comparing the outcomes for people who get chemotherapy and radiation followed by experimental immunotherapy to those who get chemotherapy and radiation followed by observation.
Seeking men and women with pancreatic cancer for a study of an experimental device used along with chemotherapy to evaluate whether it decreases cancer cell growth.
Study Of The Addition Of An Investigational Drug To Treatment Following Stem Cell Transplant For Multiple Myeloma
Seeking men and women who have had stem cell transplant for their multiple myeloma for a study of an investigational drug to be added to the usual maintenance treatment.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Study Adding An Investigational Immunotherapy To Standard Treatment For Locally-Advanced Non-Small Cell Lung Cancer
Seeking men and women diagnosed with locally-advanced non-small cell lung cancer that can't be treated with surgery for a study of adding an investigational immunotherapy to the standard cancer treatment.
Seeking women with ovarian cancer that progressed after at least 4 cycles of treatment with platinum-based chemotherapy for a study of an investigational drug.
Study Of An Investigational Drug Combination For Advanced Ovarian, Fallopian Tube Or Peritoneal Cancer
Seeking women with advanced ovarian, fallopian tube or peritoneal cancer who have, or will have "debulking" surgery to remove as much of their cancer as possible for a study of an investigational drug given in combination with the usual post-surgery chemotherapy with paclitiaxel and carboplatin.
Seeking men and women whose non-squamous non small cell lung cancer (NSCLC) has progressed after chemotherapy for a study of an investigational drug alone or in combination with an immune drug compared to the usual chemotherapy treatment.
Seeking men and women with HER2-positive breast cancer for a study comparing the usual multi-drug chemotherapy to a single chemotherapy drug and HER-2 therapy.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeking men and women scheduled for MRI imaging for a clinical breast exam for a study comparing two dyes injected to enhance MRI images.
Seeking men and women whose non-small cell lung cancer responded or remained stable to platinum-based chemotherapy and are currently taking pembrolizumab for a study of an investigational drug combination for maintenance therapy.
Seeking men and women over the age of 70 whose pancreatic cancer has spread to other parts of their body for a study comparing two different drug combination therapies.
Study Of An Investigational Drug Combination For Initial Treatment For Metastatic Non-Small Cell Lung Cancer
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women with hormone receptor positive/ human epidermal growth factor receptor 2-negative (HR+/HER2-) locally advanced inoperable or metastatic breast cancer for a study of an investigational drug combination.
Seeking men and women whose non-small cell lung cancer has spread or stopped responding to treatment and whose cancer has been tested and found to have a specific mutation in the KRAS gene known as KRAS (G12C) for a study of an investigational drug for targeted treatment against the KRAS (G12C) mutation.
A Study Comparing Medications In Patients 70 Years Of Age Or Younger With Untreated Mantle Cell Lymphoma
Seeking men and women 70 years of age or younger with untreated mantle cell lymphoma (MCL) to help determine which combination of cancer drugs most effectively treats their (MCL).
Seeking men and women 18 years of age and older who have chronic myeloid leukemia (CML) in chronic phase (CP) with and without the T315I mutation, to determine how well the treatment with asciminib works compared to previously used therapies.
Study Of An Investigational Drug Combination For Microsatellite Stable Recurrent Or Persistent Endometrial Cancer
Seeking women with microsatellite stable (MSS) recurrent or persistent endometrial cancer (EC) that has been treated with between one and three different types of chemotherapy for a study of an investigational drug combination to prevent the cancer from progressing.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
Seeking women 18 years or older with confirmed ovarian cancer who have previously received treatment, for participation in a study of an investigational drug for subjects with recurrent ovarian cancer that has failed previous treatment
Seeking men and women who have been diagnosed since January 1, 2020, with metastatic non-small cell lung cancer and have been or will be treated with immunotherapy, chemotherapy or a combination of the two for a study to develop a tool to help guide treatment decisions.
A Study Of An Investigational Drug, In Combination With Other Drugs, For Certain Types Of Prostate Cancer
Seeking men 18 years of age or older, for participation in a study of an investigational drug called Relugolix in combination with other drugs, for certain types of prostate cancer.
Seeking men and woment 18 years of age or older who have been diagnosed with recurrent glioblastoma multiforme and who have failed standard first line therapy.
Study Of An Investigational Drug Combination For Relapsed Or Refractory Diffuse Large B-Cell Lymphoma
Seeking men and women aged 18-65 years whose large B-Cell lymphoma has not responded or come back after treatment for a study of an investigational drug combination.
Seeking men and women with untreated metastatic anal cancer for a study on whether adding an immune checkpoint inhibitor drug to the usual chemotherapy helps prevent the cancer from getting worse.
Seeking men and women aged 18 and older whose non-small cell lung cancer has come back or has grown after receiving immunotherapy treatment and who are not a candidate for other biomarker-matched treatment studies for a study of an investigational drug combination.
Seeking men and women with metastatic cancer that has spread to their brain and progressed or grew back after treatment for a study of an investigational immunotherapy drug based on the gene type and source of the original cancer to prevent growth of metastatic tumors in the brain.
Seeking men and women 18 years of age or older, with kidney or thyroid cancer who are taking medications that help stop the spread of these cancers to look at the effects of blood pressure and blood pressure monitoring related to these medications.
Study Of Moderna Covid-19 Vaccine In Patients Who Have Had A Solid Organ Transplant, As Well As Healthy Volunteers
Seeking men and women over 18 years of age to determine the effectiveness of the Moderna COVID-19 vaccine in this patients who have had a solid organ transplant, kidney or liver, and health volunteers.
A Study Examining Strategies To Reduce The Formation Of Blood Clots In Hospitalized Adults With Covid-19
Seeking men and women 18 years of age or older who have been hospitalized with COVID-19 for study on ways to prevent or reduce the formation of blood clots in the patients.
Seeking men and women 18 years of age or older who have been diagnosed with and currently have mild or moderate symptoms of COVID-19 to better determine what types of medications may best treat COVID-19.
Seeking teens aged 15-18 years old who were enrolled in the ELGAN study of premature infants between April 2002 and August 2004 for a follow-up study of health and developmental progress.
Seeking children aged between 3-10 years (up to 11 for boys) with pediatric growth hormone deficiency for a study comparing an investigational drug taken by mouth to the usual treatment given by daily injections.
We are collecting data and biological samples from people with infectious or inflammatory conditions of the bowel such as celiac disease, colitis, and Inflammatory Bowel Disease (IBD) and from people who do not have bowel disease to get a better understanding of these diseases.
Seeking people whose recurrent Clostridium difficile (C. diff) infection has not responded to standard antibiotic treatments for a study to see if fecal microbiota transplantation is effective for treating C. diff infection.
Seeking men and women who are experiencing recurring fluid buildup in their abdomen due to liver cirrhosis for a study of an implanted investigational device to drain the excess fluid.
Seeking men and women aged 50 and older who will be transferred to a long-term care facility, have been a resident of a long-term care facility for more than one month, or who live in the community and attend senior center programs for a study of the gut microbiome to better understand risk factors for Clostridium Difficile (an intestinal infection that causes severe diarrhea)
Seeking men and women with diarrhea caused by a clostridium difficile (c-diff) infection for a study of an investigational oral drug.
Study To Reduce The Risk Of Clostridium Difficile (C-Diff) Infection Among Long-Term Care Facility Patients
Seeking men and women aged 65 and older for a study of changes in the microbiome in the intestines of seniors when they move into a long-term care facility.
Seeking men and women aged 40 and older scheduled to undergo a screening colonoscopy in the next 90 days for a study of a stool sample collection kit for colorectal cancer.
This research is collecting data on nicotine cravings in patients with chronic pancreatitis who smoke cigarettes.
This study is looking at an investigational treatment for patients who have been diagnosed with or have signs and symptoms of moderately to severely active Crohn’s disease.
This study is for patients diagnosed with moderately to severely active Crohn’s disease who have recently completed research study Receptos-3201 or Receptos-3202.
This study is for patients diagnosed with moderately to severely active Crohn’s disease who have recently completed a research study with the study drug.
People who have shown signs of bleeding in their stomach or intestines sought for a study of a video camera capsule to diagnose gastrointestinal bleeding.
Seeking healthy volunteers who either drink less than 1 drink per week on average or at least 3 drinks per day for a study collecting biological samples (blood, urine, and stool) and health information to better understand alcoholic hepatitis.
Seeking men and women for whom their doctor has ordered an upper endoscopy to diagnose upper gastrointestinal symptoms for a study of an investigational imaging device.
Seeking people aged 12-75 with eosinophilic esophagitis causing swallowing problems (dysphagia) for a study of an investigational drug.
Seeking people aged with Exocrine Pancreatic Insufficiency (EPI) due to Cystic Fibrosis for a study of two investigational drugs.
Children and adults who either have macular degeneration or are closely related to someone who has macular degeneration are sought for a study of macular degeneration and other related ocular disorders to prevent visual loss and blindness for current and future generations
Seeking adult male and female healthy volunteers for a national research program enrolling one million people across the U.S. to help build one of the most diverse health databases in history.
A Study Comparing Investigational Drug With An Already Approved Drug For Advanced Or Recurrent Endometrial Cancer
Seeking women at least 18 years of age with confirmed or recurrent endometrial cancer for study of an investigational drug
Stroke survivors aged 50 and over sought for a study to develop and test a wearable sensor to monitor for atrial fibrillation (abnormal heartbeats)
Study Of The Differences Between People Having A Heart Attack And People Suffering Stress Cardiomyopathy
Seeking men and women who are experiencing symptoms of a heart attack including chest pain and shortness of breath for a study of the effect of stress on heart function and the development of stress cardiomyopathy.
Seeking adult patients whose doctor has ordered a test called a Cardiac Catheterization to check for and possibly fix blockages in the heart. The doctor performing the cardiac catheterization will decide which patients who volunteer for the study are suitable participants.
Seeking men and women over the age of 18 who have been diagnosed with an aortic aneurysm (bulging of the vein that carries blood to your heart) that because of their anatomy can't be treated using an FDA-approved graft. This study would use endografts that are customized by the doctor to the anatomy of each patient to treat these complex aortic aneurysms.
Seeking men & women 18 years old and over who have a cardiomyopathy (impairment of your heart muscle strength) from coronary artery disease (hardening of the arteries).
Seeking men and women whose carotid arteries have narrowed for a study of an intense medical management plan to reduce risk factors for stroke including high blood pressure, high cholesterol, diabetes, and smoking.
Seeking men and women who are within 10 hours from the time they started to have stroke symptoms for a study of how well people who get the investigational drug in additional to the usual treatment recover compared to people who get a medicine without any active drug (placebo) in addition to the usual treatment.
Seeking men and women diagnosed with severe aortic valve stenosis for a study of an investigational device to replace the aortic valve.
Volunteers who are at risk for having heart disease, taking aspirin, and will be or have already undergone a cardiac catheterization sought for a study of how the body makes blood clots and its effect on the risk for heart attack and stroke.
Seeking men and women who are about to start a taking a pill to help thin their blood (called an anticoagulant) for a study of whether adding a clinical pharmacist to the study team improves care.
Study Of An Investigational Device To Remove Blood Clots For People Who Are Experiencing An Ischemic Stroke
Seeking men and women experiencing an ischemic stroke caused by a blood clot blocking blood flow to a part of the brain and causing a large amount of brain damage for a study comparing treatments to remove the blood clots.
Seeking men and women with peripheral artery disease (PAD) causing pain in the legs when walking or climbing stairs for a study of an investigational dietary supplement combination to improve blood flow.
Seeking men and women 18 years of age and older who have had an acute ischemic stroke within the past 12 hours for participation in a study of an investigational drug to help determine if an investigational drug can help prevent damage to brain cells.
A Study Looking At Rehabilitation Using Mobile Home Health In Holder Adults After Hospitalization (Resilient)
Seeking men and women 65 years of age or older to understand whether a personalized care plan for home exercise, coupled with the use of mobile health technology following a hospital admission for a heart attack or a cardiovascular procedure can prevent decline and improve health.
Seeking men and women with a blood clot causing Deep Vein Thrombosis for which their doctor has recommended surgical treatment for a study of an investigational device inserted into the vein using a catheter to remove the clot.
Seeking blood samples from healthy volunteers and volunteers who have various autoimmune diseases, like type 1 diabetes
Seeking men and women who are willing to donate fat cells for a study of the difference between fat cells collected from healthy volunteers and people who have type 2 diabetes.
Seeking men and women with type 2 Diabetes Mellitus to participate in an expert panel for a study to develop and test a technology to help people manage their diabetes.
Seeking participants between the ages of 6 and 65 to participate in a study about appetite and weight related to a specific gene variation and whether a specific drug can control this.
Seeking participants between the ages of 6 and 65 to participate in a study about appetite and weight related to a specific gene variation and whether a specific drug can control this.
Study of whether treatment of congenital cytomegalovirus (cCMV) in infants who have experienced hearing-impairment reduces the loss in left or right ear hearing.
Seeking children who have been diagnosed with influenza in the past 7 days and healthy children willing to donate a blood sample for a study of how influenza affects blood cells of children.
We are seeking healthy adult male and female volunteers who may have been previously infected with a number of viruses to provide blood, oral, and nasal samples. We want to develop new ways to detect and measure viruses, and study the way the immune system fights infection of viruses.
Study Of An Investigational Drug To Prevent Hospitalization For People Newly Diagnosed With Covid-19
Seeking men and women who have tested positive for COVID-19 within the past 10 days and within 7 days of first experiencing COVID symptoms for a study of an investigational drug.
Seeking healthy children younger than 12 for a study of an investigational vaccine against COVID-19.
Seeking men and women aged 18 and older who get their care at UMass Memorial clinics to participate in a focus group on outreach materials for COVID-19 vaccination.
Seeking men and women aged 18 to 30 for a study of an investigational vaccine to prevent the Epstein-Barr virus, which is the main cause of infectious mononucleosis.
Seeking children younger than 18 who have COVID-19 and are at risk for serious disease but have not been hospitalized for a study of an investigational drug.
Seeking healthy adults and adults who have been suffering influenza-like illness for no more than 14 days for a study of how the flu or flu-like infections affect their blood cells.
Seeking adults and children for a study testing the accuracy of investigational devices to diagnose COVID-19.
Seeking men and women aged 50 and older hospitalized with pneumonia caused by a COVID-19 infection for a study of the long-term effects of COVID-19 on memory and thinking.
Seeking men and women willing to provide additional nasal, saliva and blood samples when being tested for COVID-19 for a biorepository to support development of tests for COVID-19 and studies of how COVID-19 causes disease in people.
Seeking men and women aged 18 and older who have not had COVID-19 or been vaccinated for a study of an investigational device used at home to detect COVID-19 in nasal swabs.
Seeking neonates (babies up to 28 days old) for a study collecting blood samples to assess a lab test to diagnosis the blood infection sepsis.
Seeking men and women who have previously received two doses of the Moderna COVID-19 vaccine for a study of a booster vaccine that is slightly different than the original Moderna COVID-19 vaccine.
Seeking men and women with either normal airways or airways that have been difficult to manage while under anesthesia for a study of a voice test might reliably predict people whose airways may be difficult to manage during an operation.
Seeking intubated (tube placed in someone's throat to help them breathe) people for a study of an investigational device to improve their communication with caregivers.
Study Of Body Fluid Samples From People With Cystic Fibrosis To Look At The Body's Response To Infection\ Inflammation
Seeking people with Cystic Fibrosis aged 12 and older for a study of blood, sputum, and/or leftover fluid collected during your bronchoscopy to look at how your body responds to infection or inflammation.
This is an observational study of patients with cystic fibrosis. Any patient diagnosed with cystic fibrosis can participate.
Preterm Infants diagnosed with pauses in breathing (apnea of prematurity) and treated for intermittent hypoxia using caffeine sought for study of longer-term caffeine treatment
Seeking people aged 12 and older with stable cystic fibrosis disease for a study of an investigational drug combination to improve pulmonary function and other symptoms.
Seeking men and women aged 12 and older with cystic fibrosis of specific genotypes for a study of whether adding an investigational drug to elexacaftor (ELX)/tezacaftor (TEZ)/ivacaftor (IVA) treatment improves lung function.
We are collecting blood samples from healthy controls and Systemic Lupus Erythematosus (SLE) patient samples to learn more about potential molecules that are responsible for the development of Lupus.
Seeking men and women who have been diagnosed with schizophrenia or schizoaffective disorder and a substance use disorder for a study of an anti-psychotic medication to see it helps reduce substance cravings.
Study comparing two interventions to reduce suicidal behaviors and thoughts for people admitted to the emergency department or psychiatric unit of the hospital who recently attempted suicide or had suicidal thoughts
Men and women who arrive at the emergency department seeking care for either a medical or psychiatric condition may be asked to participate in a study of a screening survey to identify people at risk for suicide.
Seeking deaf adults and ASL users who is experiencing problems with alcohol use and trauma for an experimental intervention that we hope will reduce symptoms of addiction.
Seeking veterans with post-traumatic stress disorder (PTSD) or PTSD symptoms for a study of an intervention to see if observing and caring for injured or orphaned wildlife at a wildlife rehabilitation center helps to reduce PTSD symptoms.
Seeking participation from people aged 12 and older visiting the emergency room, hospital or outpatient clinic at UMass Memorial.
Seeking transgender patients who receive either hormone replacement therapy (HRT) alone or gender confirmation top-surgery in addition to HRT for a study of the impact of treatment.
Seeking teens who live with Autism Spectrum Disorder (ASD) for a study to image their brains using magnetic resonance imaging (MRI) to better understand how their brains function.
Adults currently suffering from symptoms of post-traumatic stress disorder are invited to participate in a research study to determine the effectiveness and safety of an investigational drug for post-traumatic stress disorder (PTSD).
Seeking men and women with treatment resistant depression for a study of an investigational nasal spray.
Study Of An Investigational Drug For Social Performance Of Adolescents With Autism Spectrum Disorder
Seeking teens aged 13-17 with autism spectrum disorder for a study of whether an investigational drug affects the level of the chemical GABA in the brain and if it improves social performance.
A Study To Compare Standard Chemotherapy To One Or More Investigational Drugs For Patients With Newly Diagnosed Aml
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.
A Study Comparing Two Ways To Address Spontaneously Breathing In Newborns With Respiratory Distress Syndrome (Rds)
Seeking male and female preterm newborns who have been diagnosed with Respiratory Distress Syndrome.
This study is collecting tissue and information from pregnant women who are having cesarean births to gain a better understanding of how the uterus functions.
Pregnant women who are in their late 2nd to 3rd trimester who have high blood pressure are sought for a study to develop a screening test for preeclampsia in pregnant women. We will collect samples of your blood, urine, and saliva to see if we can detect levels of a protein that would help accurately predict who will get preeclampsia.
Pregnant women with either normal or high blood pressure sought for a study of the effects of high blood pressure during pregnancy. The study will assess whether future cardiovascular disease or serious pregnancy complications like preeclampsia can be better detected & prevented.
Seeking pregnant women with chronic hypertension, gestational hypertension or a history of hypertensive disorders of pregnancy for a brief survey of their experiences and approaches to healthy eating.
Seeking men and women 60 years of age for the study of an investigational vaccine against Respiratory Syncytial Virus
We are studying how skin diseases occur in the skin, including how immune cells choose to initiate disease as well as what causes them to enter the skin.
Seeking children and adults with an autoimmune skin disease such as vitiligo, atopic dermatitis, alopecia areata, lupus, psoriasis, or scleroderma, and adult healthy volunteers willing to donate skin and blood for a study of autoimmune diseases of the skin.
Seeking men and women who take blood thinning medication and who will have Mohs surgery to remove skin cancer cells for a study of an investigational drug to reduce bleeding during surgery.
Seeking men and women with a skin condition called atopic dermatitis, which is a more severe type of eczema, for a study of a skin biopsy sampling technique called microsampling.
Seeking men and women with or without an inflammatory skin disease ( such as cutaneous lupus erythematosus, dermatomyositis, atopic dermatitis, alopecia areata, scleroderma, eczema, psoriasis, vitilago, or drug hypersensitivity) for a study to learn more about skin diseases and their response to light.
Seeking men and women with vitiligo for a study of an investigational drug to see if it is safe and effective in returning normal skin color to white spots for people with vitiligo.
Seeking children under 18 years of age and healthy volunteers from 6 to 18 to study the skin immune system.
Seeking men and women 18 years of age or older who have had a stroke caused by bleeding in their brain to help determine is a new drug called recombinant factor VIIa (rFVIIa) can improve outcomes compared to a placebo when added to the standard care provided after a stroke.
Seeking men and women over 18 years of age who have had a stroke within the past 24 hours for the study of an investigational device.
Comparing The Effects Of Different Levels Of Nursing Care Monitoring For Patients With Acute Ischemic Stroke (Optimist)
Men and women over 18 years old who have a diagnosis of acute ischemic stroke (AIS) and have been given intravenous thrombolysis (IVT) treatment.
Seeking men and women 18-85 years of age who have had an acute ischemic stroke caused by blood clots in the brain to evaluate a new device that is intended to remove these clots.
Suicide Risk And Opioid Use Disorders: Administrative Supplement To The System Of Safety (S O S) Study
Seeking adults and children 12 and older who have come to the hospital with either suicide risk or who use opioids in order to learn more about suicide risk and opioid use disorders and the medical care these individuals receive.
Seeking children who have been referred for outpatient ear surgery for a study comparing two drugs for managing pain and preventing emergence delirium when they are waking up from anesthesia following surgery.
Seeking men and women with low frequency hearing for a study of a investigational cochlear implant device to improve hearing performance.
Seeking men and women who will be admitted to the minimally invasive surgery service at UMass Memorial for a study of how walking after surgery helps with healing.
Seeking men and women aged 18 and older for a study of sensors worn on or applied to the skin to measure pain.
Seeking men and women aged 18-85 whose degenerative disc disease or spondylolisthesis requires spinal fusion surgery with bone grafting for a study of a synthetic bone graft.
Seeking men and women who will be undergoing surgery or being cared for in an intensive care unit and who will require an intra-arterial catheter for a study of a investigational device similar to a wristwatch to continuously monitor blood pressure.
Seeking men and women whose doctor has scheduled them for surgery to repair a colovesical fistula (CVF) for a study of the timing of foley catheter removal following surgery.
Seeking men and women aged 18 and older who will be undergoing endovascular surgery to treat and aneurysm or blockage in their artery for a study to improve imaging needed for the surgery.
Seeking men and women aged 65 or older who have been discharged from the hospital within the past month for a survey of their health and use of healthcare following their discharge from the hospital.
A Study Looking To Reduce The Rate Of Postoperative Urinary Retention Rates In Men Who Have Had Thoracic Surgery (Pour)
Seeking men 60 years of age or older who will undergo inpatient thoracic surgery.
Seeking men and women, 18-80 years of age, who have experienced blunt head trauma with loss of consciousness for study of a new device to detect traumatic brain injury through blood testing.
Seeking adult men and women who have a wound that their medical provider has recommended be treated with a surgical procedure.
A Study Of An Investigational Drug In Subjects With Moderately To Severely Active Ulcerative Colitis.
Seeking Men and Women over 18 years of age with moderately to severely active ulcerative colitis for participation in a study of an investigational product called Efavaleukin Alfa