Seeking men and women with Systemic Lupus Erythematous(SLE) and Lupus Nephritis for a biorepository study to collect health information and biological samples to help researchers learn more about the disease and help design future studies.
206 Studies found
Seeking people with a bleeding disorder such as Hemophilia or Von Willebrand Disease for a registry to collect health data to address the needs and challenges of people living with bleeding disorders.
Seeking men & women over 18 years old who have a blood disorder or malignancy to investigate normal and abnormal cell growth.
Men and women over 16 years old undergoing transplantation with unlicensed CBUs (cord blood units) will be enrolled. Cord blood units not meeting FDA requirements or not yet approved by the FDA may be used for transplant if the transplant is done as part of a study.
Adult male and female U.S. recipients of allogeneic or autologous HSC transplants or cellular therapies are eligible to participate in the NMDP Research Sample Repository.
Seeking boys and men aged 12-50 with Becker Muscular Dystrophy for a study of the safety and effectiveness of an investigational drug to prevent muscle weakness.
Study Of An Investigational Drug To Preserve Muscle Function In Boys With Duchenne Muscular Dystrophy
Seeking boys aged 4 to 16 for a study of an investigational drug to increase dystrophin protein levels in muscles.
Seeking men and women with upper limb spasticity that affects the movement in their arms and/or hands for a study comparing two treatments that have already been approved by the Food and Drug Administration (FDA).
Seeking adults aged 18 and older who either have Facioscapulohumeral Muscular Dystrophy (FSHD) or are healthy volunteers for a study to identify genetic biomarkers for the disease and better understand what causes it, and why symptoms vary widely among people who have it.
Seeking boys and men with Duchenne muscular dystrophy (DMD) or Becker Muscular Dystrophy (BMD) to provide samples including blood, plasma, serum, urine, as well as the remainders of tissue samples collected as part of their usual clinical care for a biorepository.
Seeking male participants aged 10-21 years of age who have been diagnosed with Duchenne Muscular Dystrophy (DMD) for participation in an imaging study.
Study Of An Investigational Implant To Prevent The Discs Between Backbone Vertebrae From Being Pushed Out (Herniating)
Seeking men and women whose doctor has recommended surgery to relieve pain resulting from damage to a disc in their back being pushed out of place (herniated) for a study of an investigational device to prevent the disc from reherniating.
This study is intended to collect data from medical records on patients who have Duchenne Muscular Dystrophy
Seeking adults with degenerative spondylolisthesis with lumbar spinal stenosis whose doctors have recommended back surgery to address the pressure on your spinal cord or spinal nerves
Seeking men and women with moderate to severe rheumatoid arthritis that has not responded or has stopped responding to biologic or disease-modifying Anti-Rheumatic drugs for a study of an investigational device.
Seeking men and women whose active systemic lupus erythematosus (SLE) is being treated with non-biologic therapy for a study of an investigational drug.
Study Comparing Two Different Treatments For Rheumatoid Arthritis That Has Not Responded To Tnf-Biologic Treatment
Seeking men and women whose rheumatoid arthritis has not responded to TNF-biologic treatment for a study comparing two different types of treatments (non-TNFi-biologic and tsDMARDs).
Seeking men and women whose broken arms or legs will need to be treated with surgery for a study of what treatment practices best prevent infection.
Seeking adults who have inflammatory arthritis and who are willing to provide data by answering questionnaires, giving a blood sample and donating leftover tissue samples for a study to help researchers better understand inflammatory arthritis.
Seeking men and women over the age of 65 for a study of an investigational device to screen for cognitive impairment.
A Study To Look At What Makes People Interested In Being A Part Of Parkinson's Disease Research (Fire-Up Pd)
Seeking men and women 18 years of age or older to complete surveys to help determine how people decide to participate in Parkinson's disease research
Seeking men and women with Adrenomyeloneuropathy for a gene therapy study to try and correct gene defects so that nerve cells can create proteins needed to prevent damage to spinal cord cells and nerves.
Seeking men and women who undergo repeated MRI scans with contrast for a study of the longterm effect of the contrast on motor and cognitive function over a period of 5 years
Seeking people aged 12 and older who have a form of epilepsy called Status Epilepticus, causing near constant seizures, for a study to determine if an investigational drug added to the usual therapy helps reduce seizures.
Seeking men and women aged 18-55 for a study of an investigational drug for primary progressive multiple sclerosis.
Seeking men and women with multiple sclerosis for a study of how common sleep apnea is and whether sleep apnea affects MS symptoms.
Seeking women and men who have started ocrelizumab treatment for their Multiple Sclerosis (MS) within the past month or people whose MS is being being treated with therapies other than ocrelizumab for a study looking at the incidence of cancer in the future.
This is a registry to collect medical record information from people living with Multiple Sclerosis (MS) to better understand the disease and develop new treatments
Seeking men and women with relapsing multiple sclerosis whose doctors has decided to start treatment with clabridine tablets because other pills were not working well.
Seeking men and women whose multiple sclerosis has not responded well to previous treatment and whose doctor has decided to start treatment with cladribine tablets and stop treatment with an injectable drug.
Seeking men and women aged 18-80 who need treatment for an intracranial aneurysm (a bulge in a blood vessel in the brain that could rupture and bleed into the brain) for a study of a device called a coil to prevent rupture.
Seeking men and women who have had a recent stroke or transient ischemic attach (TIA) often called a "mini-stroke" for a study of the benefits of using a continuous positive airway pressure (CPAP) machine while sleeping.
Seeking men and women with early Parkinson's Disease for a study of an investigational drug to slow the development of disease symptoms.
Seeking men and women with atrial fibrillation and a recent brain hemorrhage causing increased risk for stroke for a study of blood thinners to reduce risk of stroke.
Seeking men and women with multiple sclerosis (MS) that hasn't responded to previous treatment for a study of an experimental drug.
Seeking men and women who have a wide-necked, bifurcated saccular intracranial aneurysm that requires endovascular treatment for a study of an investigational device.
Seeking men and women 18 years of age or older with relapsing multiple sclerosis (RMS) for participation in a study comparing an investigational drug called fenebrutinib to a drug called teriflunomidie.
Seeking men and women whose doctor has recommended treatment for an acute ischemic stroke for a study collecting blood clots and medical information to better understand how to treat and prevent acute ischemic stroke.
Seeking men and women aged 50 and older who have had bleeding in the brain (brain hemorrhage) for a study comparing continuing or stopping statin drug use treatment on the risk of having another brain hemorrhage.
Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.
Seeking men and women who are participating in the ARCADIA stroke prevention trial for a study of the effect of the study drugs Apixaban and Aspirin on the occurrence of silent strokes and memory loss.
Seeking people with Parkinson's disease and healthy volunteers for a study of how speech changes depending on PD symptoms, effects of medication and genetics.
Study Of Multiple Investigational Drugs To Prevent Progression Of Amyotrophic Lateral Sclerosis (Als)
Seeking men and women with Amyotrophic Lateral Sclerosis (ALS) to participate in a research trial to test several different investigational treatments.
Seeking men and women aged between 18 and 80 for a study of how the brain works when making decisions when the answer is uncertain.
Study Of An Investigational Stem Cell Transplant For Treatment Resistant Relapsing Multiple Sclerosis
Seeking men and women whose multiple sclerosis has remained active despite treatment for a study comparing blood stem cell transplantation to other available treatments for multiple sclerosis.
Study Of The Effects Of Hospital Interventions Just After A Traumatic Brain Injury Affects Long-Term Outcome
Seeking men and women aged 18 and older who have been admitted to the hospital intensive care unit following a traumatic brain injury for a study of how care received in the hospital impacts long-term recovery.
Seeking volunteers who will have their brain aneurysm treated using a coil to prevent it from bursting for a study of the long term performance of the coil.
This study is enrolling men and women who have had a traumatic brain injury in order to compare outcomes when medical care is delivered based on either monitoring the pressure in the brain or monitoring both the pressure in the brain and the amount of oxygen in the brain.
Seeking men and women who are within the first few hours of experiencing an ischemic stroke (caused by a blood clot blocking blood flow to the brain) for a study comparing medication combinations to reduce the impact of the stroke.
Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.
Seeking women scheduled for a routine screening mammogram for a study comparing Artificial Intelligence (AI) software to standard guidelines for predicting breast cancer risk.
A Study Of Different Imaging Standards In Breast And Prostate Cancer Tissue (Dti Breast And Prostate)
Seeking men and women over 18 years of age who are scheduled to undergo magnetic resonance imaging (MRI) for either prostate or breast cancer to look at a new imaging method.
Seeking men and women with newly diagnosed glioblastoma for a study of an investigational device used in combination with chemotherapy and radiation.
Seeking men and women getting chemotherapy with Carboplatin and Paclitaxel for a study of an investigational drug to prevent neuropathy.
Seeking people aged 1-21 years old with certain kinds of solid tumor cancer for a study of an investigational drug.
Seeking people aged up to 21 years for a study of decreasing the length of chemotherapy treatment for people with low risk rhabdomyosarcoma and increasing the length of chemotherapy treatment for people with high risk rhabrhabdomyosarcoma.
Seeking men and women with metastatic cancer that has spread to their brain and progressed or grew back after treatment for a study of an investigational immunotherapy drug based on the gene type and source of the original cancer to prevent growth of metastatic tumors in the brain.
Seeking men and women whose meningioma (cancer of the brain covering) has gotten bigger or grew back after treatment for a study of whether cancer drugs targeting tumors based on their genetics is better, the same, or worse than the standard treatment for meningiomas.
Seeking men and women with untreated metastatic anal cancer for a study on whether adding an immune checkpoint inhibitor drug to the usual chemotherapy helps prevent the cancer from getting worse.
A Study To Determine If Participants With A Certain Cancer Can Stop Taking A Specific Medication (Aaml18p1)
Seeking male and female participants under the age of 25, who were diagnosed with Chronic Myeloid Leukemia before the age of 18, to determine if they can stop taking their TKI medication and remain in remission as well as if restarting TKI will re-achieve remission.
Study Of An Investigational Drug For Advanced Relapsed, Refractory, Or Resistant Hematological (Blood) Cancer
Seeking men and women with advanced relapsed, refractory, or resistant hematological (blood) cancer with an IDH mutation that has not responded or stopped responding to prior treatment for participation in a study of an investigational drug.
Seeking men and women who have been diagnosed since January 1, 2020, with metastatic non-small cell lung cancer and have been or will be treated with immunotherapy, chemotherapy or a combination of the two for a study to develop a tool to help guide treatment decisions.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Seeking men and women who have had a lung nodule detected during imaging for collection of nasal swab and blood samples.
Seeking adults who underwent lung cancer screening within the past three years to complete a survey and interview about this process in order to develop a telehealth intervention and improve adherence to screening follow-up.
Seeking people aged 30 and younger newly diagnosed with diffuse anaplastic Wilms tumor, a type of cancer that occurs in the kidney, for a study of experimental treatment regimen because no standard treatment regimen currently exists.
Seeking men and women who are current smokers for a study of motivational text messages to help people stop smoking.
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Study Of Chemotherapy For Children And Young Adults With High-Risk B-Cell Acute Lymphoblastic Leukemia (B-All)
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking men and women aged 18 and older whose colon, peritoneal, or rectal cancer will be treated with surgery (resectable) for a study of an investigational drug to make the cancer cells glow under infrared light.
Study Of An Investigational Drug For Relapsed Or Refractory Cd22+ B-Acute Lymphoblastic Leukemia (B All)
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
Seeking people aged 3 to 25 with newly-diagnosed high-grade glioma whose brain tumor has been genetically tested to show that it does not have the H3, K27M and BRAF mutations for a study of an investigational drug. The study will compare whether adding the investigational drug to radiation and maintenance therapy is better than the usual treatment.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
This study is for patients who may have neuroblastoma, a tumor of nerve cells typically found in the stomach, chest or neck of young children. This is a data and sample collection study to help us better understand this disease.
This study is looking at using different experimental treatment methods for children diagnosed with Acute Myeloid Leukemia (AML) and Down Syndrome (DS) based on how well they respond to their first treatment.
Seeking male and female children ranging from 0-18 months of age diagnosed with non-high risk neuroblastoma.
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking men and women who have been prescribed immunotherapy to treat their cancer for a study observing the side effects of immunotherapy.
Seeking men and women with urothelial (renal pelvis, ureter, bladder, or urethra) cancer that has spread to other places in the body (metastatic) for a study of an investigational drug combination.
Seeking people who have who have already taken endocrine therapy for two to five years for their early-stage ER+/HER2- breast cancer and have a higher-than-average risk for their cancer to return for a study to compare the investigational drug to standard hormone therapy.
Study Of An Investigational Drug For Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma Or Non-Hodgkin Lymphoma
Seeking men and women who have a type of cancer that affects the B-cells (a type of white blood cells) in your blood that has not responded to, or who could not tolerate, the standard treatments normally given for this type of cancer for a study of an investigational drug.
Seeking men and women whose multiple myeloma has returned or gotten worse despite treatment for a study comparing investigational drug combinations.
Study Of Ending Hormone Treatment After An Exceptional Response To Metastatic Prostate Cancer Hormone Treatment
Seeking men whose metastatic prostate cancer has responded exceptionally well to therapy that included a medication to decrease testosterone and a medication to prevent growth signals in the body from male hormones including testosterone for a study of interrupting hormone treatment to allow testosterone levels to recover.
Study Of An Investigational Drug For Men With High-Risk Metastatic Hormone-Sensitive Prostate Cancer
Seeking men with prostate cancer that has spread to other parts of their body (metastatic) that has been treated with androgen deprivation therapy (ADT) for a study of an investigational drug.
Seeking men and women who have Multiple Myeloma (MM) and will undergo Autologous Stem Cell Transplant (ASCT) as a form of treatment for a study of an investigational drug to help collect blood stem cells.
Seeking men and women whose multiple myeloma has returned following treatment or did not respond to treatment for a study of an investigational drug.
Seeking men and women 18 years of age or older, with kidney or thyroid cancer who are taking medications that help stop the spread of these cancers to look at the effects of blood pressure and blood pressure monitoring related to these medications.
Study Of An Investigational Drug And Standard Chemoradiation Therapy For Locally Advanced Non-Small Cell Lung Cancer
Seeking men and women whose locally-advanced stage III Non-small Cell Lung Cancer (NSCLC) can not be treated with surgery for a study of adding an investigational drug to the standard chemoradiation therapy.
IRONMAN Registry aims to collect detailed information about the participants in the study at the time of enrollment and to follow their medical care to better understand what treatments work and where there are unmet needs in their treatment.
Seeking men and women over 18 years of age who have relapsed or refratory B-cell lymphoma after first line chemoimmunotherapy for participation in a study looking at an investigational drug in combination with other drugs
Seeking men and women with with Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia for a study of an investigational drug to reduce spleen volume.
Study Of An Investigational Drug Combination For Relapsed Or Refractory Diffuse Large B-Cell Lymphoma
Seeking men and women aged 18-65 years whose large B-Cell lymphoma has not responded or come back after treatment for a study of an investigational drug combination.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
A Study Investigational Drugs To The Standard Of Care In Participants With Metastatic Esophageal Carcinoma
Seeking men and women over 18 years of age who have been diagnosed with metastatic esophageal carcinoma for a study of two drugs in addition to chemotherapy as compared to the standard of care.
Study Of An Investigational Drug Combination For Microsatellite Stable Recurrent Or Persistent Endometrial Cancer
Seeking women with microsatellite stable (MSS) recurrent or persistent endometrial cancer (EC) that has been treated with between one and three different types of chemotherapy for a study of an investigational drug combination to prevent the cancer from progressing.
Study Of An Investigational Drug Added To Usual Treatment For Relapsed Or Refractory Multiple Myeloma
Seeking men and women whose multiple myeloma has returned or has not responded to their most recent treatment for a study adding an investigational drug to the usual treatment.
Seeking men and women whose non-small cell lung cancer has spread or stopped responding to treatment and whose cancer has been tested and found to have a specific mutation in the KRAS gene known as KRAS (G12C) for a study of an investigational drug for targeted treatment against the KRAS (G12C) mutation.
Study Of An Investigational Drug Combination For Initial Treatment For Metastatic Non-Small Cell Lung Cancer
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Men and women with advanced HPV throat cancer sought for a study comparing the outcomes for people who get chemotherapy and radiation followed by experimental immunotherapy to those who get chemotherapy and radiation followed by observation.
Study Of Immunotherapy Alone Or In Combination With Chemotherapy For Advanced Nonsquamous Non-Small Cell Lung Cancer
Non-squamous non-small cell lung cancer patients whose cancer has been tested to be PD-L1 positive (a kind of tumor marker) sought for study comparing two usual approaches to treatment.
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
This study is looking to compare different surgical options for treating patients with rectal cancer.
Seeking adult men & women whose tumor cells have a change in a gene called ALK that causes the cells to grow and spread.
A Study Examining Strategies To Reduce The Formation Of Blood Clots In Hospitalized Adults With Covid-19
Seeking men and women 18 years of age or older who have been hospitalized with COVID-19 for study on ways to prevent or reduce the formation of blood clots in the patients.
Seeking men and women 18 years of age or older who have been diagnosed with and currently have mild or moderate symptoms of COVID-19 to better determine what types of medications may best treat COVID-19.
Seeking men aged 18-45 with Fragile X Syndrome for a study of an investigational drug.
Seeking infants admitted to the NICU with an unexplained likely genomic illness for a study of the benefit of genomic testing on their care.
Seeking teens aged 15-18 years old who were enrolled in the ELGAN study of premature infants between April 2002 and August 2004 for a follow-up study of health and developmental progress.
Study To Reduce The Risk Of Clostridium Difficile (C-Diff) Infection Among Long-Term Care Facility Patients
Seeking men and women aged 65 and older for a study of changes in the microbiome in the intestines of seniors when they move into a long-term care facility.
Seeking men and women aged 50 and older who will be transferred to a long-term care facility, have been a resident of a long-term care facility for more than one month, or who live in the community and attend senior center programs for a study of the gut microbiome to better understand risk factors for Clostridium Difficile (an intestinal infection that causes severe diarrhea)
Seeking people whose recurrent Clostridium difficile (C. diff) infection has not responded to standard antibiotic treatments for a study to see if fecal microbiota transplantation is effective for treating C. diff infection.
We are collecting data and biological samples from people with infectious or inflammatory conditions of the bowel such as celiac disease, colitis, and Inflammatory Bowel Disease (IBD) and from people who do not have bowel disease to get a better understanding of these diseases.
This research is collecting data on nicotine cravings in patients with chronic pancreatitis who smoke cigarettes.
Children and adults who either have macular degeneration or are closely related to someone who has macular degeneration are sought for a study of macular degeneration and other related ocular disorders to prevent visual loss and blindness for current and future generations
Seeking adult male and female healthy volunteers for a national research program enrolling one million people across the U.S. to help build one of the most diverse health databases in history.
A Study Looking At Whether An Investigational Drug Is Safe And Effective For Participants With Fragile X Syndrome
Seeking male participants aged 12 to less than 18 years of age for a study of an investigational drug and it's safe and effectiveness for participants with Fragile X Syndrome
Seeking boys and girls with Fragile X Syndrome who were born between 2003 and 2017 for a registry to better understand how to manage and treat Fragile X Syndrome.
Seeking men and women who get their care at UMass Memorial for a chronic health condition such as heart disease, diabetes or kidney disease for a study of an investigational device embedded in a toilet seat to remotely monitor cardiac health.
Study Of The Differences Between People Having A Heart Attack And People Suffering Stress Cardiomyopathy
Seeking men and women who are experiencing symptoms of a heart attack including chest pain and shortness of breath for a study of the effect of stress on heart function and the development of stress cardiomyopathy.
Stroke survivors aged 50 and over sought for a study to develop and test a wearable sensor to monitor for atrial fibrillation (abnormal heartbeats)
Study Looking At Safety And Effectiveness Of An Approved Device To Treat A Weakness In A Blood Vessel In The Brain
Seeking men and women 18 years of age or older who have been diagnosed with a specific type brain aneurysm for study of the long term safety of an approved device (WEB®) intended to treat this issue.
Seeking men and women 18 to 80 years of age who have been diagnosed with a specific type brain aneurysm for study of an investigational device intended to treat this issue.
Study Of An Investigational Device To Remove Blood Clots From People Experiencing An Ischemic Stroke
Seeking men and women who are experiencing ischemic stroke for a study of an investigational device to remove the blood clot using suction and restore blood flow to the brain.
Seeking men and women with heart failure due to a dilated left ventricle (heart chamber that pumps blood) for a study of an investigational device.
Seeking people aged 50 and older narrowing of their heart valve (aortic valve stenosis) for a study to improve diagnosis and treatment for aortic valve stenosis.
Seeking men and women with a blood clot causing Deep Vein Thrombosis for which their doctor has recommended surgical treatment for a study of an investigational device inserted into the vein using a catheter to remove the clot.
A Study Looking At Rehabilitation Using Mobile Home Health In Holder Adults After Hospitalization (Resilient)
Seeking men and women 65 years of age or older to understand whether a personalized care plan for home exercise, coupled with the use of mobile health technology following a hospital admission for a heart attack or a cardiovascular procedure can prevent decline and improve health.
Seeking men and women with peripheral artery disease (PAD) causing pain in the legs when walking or climbing stairs for a study of an investigational dietary supplement combination to improve blood flow.
Volunteers who are at risk for having heart disease, taking aspirin, and will be or have already undergone a cardiac catheterization sought for a study of how the body makes blood clots and its effect on the risk for heart attack and stroke.
Seeking men and women diagnosed with severe aortic valve stenosis for a study of an investigational device to replace the aortic valve.
Seeking men and women whose carotid arteries have narrowed for a study of an intense medical management plan to reduce risk factors for stroke including high blood pressure, high cholesterol, diabetes, and smoking.
Seeking men & women 18 years old and over who have a cardiomyopathy (impairment of your heart muscle strength) from coronary artery disease (hardening of the arteries).
Seeking men and women over the age of 18 who have been diagnosed with an aortic aneurysm (bulging of the vein that carries blood to your heart) that because of their anatomy can't be treated using an FDA-approved graft. This study would use endografts that are customized by the doctor to the anatomy of each patient to treat these complex aortic aneurysms.
Seeking adult patients whose doctor has ordered a test called a Cardiac Catheterization to check for and possibly fix blockages in the heart. The doctor performing the cardiac catheterization will decide which patients who volunteer for the study are suitable participants.
Seeking men and women who have been treated for episodes of low blood sugar at the UMass Memorial Diabetes Center of Excellence for a study to see if a smartwatch can sense low blood sugar.
Seeking men and women with type 2 Diabetes Mellitus to participate in an expert panel for a study to develop and test a technology to help people manage their diabetes.
Seeking men and women who are willing to donate fat cells for a study of the difference between fat cells collected from healthy volunteers and people who have type 2 diabetes.
Seeking blood samples from healthy volunteers and volunteers who have various autoimmune diseases, like type 1 diabetes
Seeking participants between the ages of 6 and 65 to participate in a study about appetite and weight related to a specific gene variation and whether a specific drug can control this.
Seeking healthy men and women volunteers aged 18-55 for a study of an investigational vaccine against Epstein Barr Virus which is the main cause of mononucleosis.
Seeking babies aged 5 to 24 months old for a study of an mRNA vaccine to prevent respiratory syncytial virus (RSV).
Seeking babies aged 12 weeks to less than 6 months old for a study of a COVID vaccine.
Seeking parents of kids aged 5-17 who receive their care at UMass Memorial for a research survey about their intentions on having their child vaccinated against COVID-19.
Seeking men and women health care workers for an observational study of the effectiveness of COVID vaccine boosters.
Seeking men and women aged 65 and older who have been hospitalized for what may be pneumonia for a study of the effectiveness of vaccines against pnuemonia.
Seeking men and women aged 18 and older who get their care at UMass Memorial clinics to participate in a focus group on outreach materials for COVID-19 vaccination.
We are seeking healthy adult male and female volunteers who may have been previously infected with a number of viruses to provide blood, oral, and nasal samples. We want to develop new ways to detect and measure viruses, and study the way the immune system fights infection of viruses.
Seeking children who have been diagnosed with influenza in the past 7 days and healthy children willing to donate a blood sample for a study of how influenza affects blood cells of children.
Seeking people aged 21 and younger who have lyme disease and likely have meningitis that has not yet been treated. To participate in a study comparing two different antibiotic treatments
Seeking neonates (babies up to 28 days old) for a study collecting blood samples to assess a lab test to diagnosis the blood infection sepsis.
Seeking healthy adults and adults who have been suffering influenza-like illness for no more than 14 days for a study of how the flu or flu-like infections affect their blood cells.
Seeking men and women with Chronic Obstructive Pulmonary Disease (COPD) for a study of an mobile digital device app to provide in-home support to manage COPD.
Study Of Body Fluid Samples From People With Cystic Fibrosis To Look At The Body's Response To Infection\ Inflammation
Seeking people with Cystic Fibrosis aged 12 and older for a study of blood, sputum, and/or leftover fluid collected during your bronchoscopy to look at how your body responds to infection or inflammation.
Seeking intubated (tube placed in someone's throat to help them breathe) people for a study of an investigational device to improve their communication with caregivers.
Seeking men and women with either normal airways or airways that have been difficult to manage while under anesthesia for a study of a voice test might reliably predict people whose airways may be difficult to manage during an operation.
Preterm Infants diagnosed with pauses in breathing (apnea of prematurity) and treated for intermittent hypoxia using caffeine sought for study of longer-term caffeine treatment
This is an observational study of patients with cystic fibrosis. Any patient diagnosed with cystic fibrosis can participate.
We are collecting blood samples from healthy controls and Systemic Lupus Erythematosus (SLE) patient samples to learn more about potential molecules that are responsible for the development of Lupus.
Seeking men and women with opioid use and mental health disorders for a study of different combinations of treatments.
Seeking men and women 18 years and older for a study of a particular therapy in decreasing negative symptoms after motor vehicle collision.
Seeking men and women who have anxiety for a user test of a phone app to help in dealing with anxiety.
Seeking transgender patients who receive either hormone replacement therapy (HRT) alone or gender confirmation top-surgery in addition to HRT for a study of the impact of treatment.
Seeking veterans with post-traumatic stress disorder (PTSD) or PTSD symptoms for a study of an intervention to see if observing and caring for injured or orphaned wildlife at a wildlife rehabilitation center helps to reduce PTSD symptoms.
Seeking deaf adults and ASL users who is experiencing problems with alcohol use and trauma for an experimental intervention that we hope will reduce symptoms of addiction.
Study comparing two interventions to reduce suicidal behaviors and thoughts for people admitted to the emergency department or psychiatric unit of the hospital who recently attempted suicide or had suicidal thoughts
Seeking men and women who have been diagnosed with schizophrenia or schizoaffective disorder and a substance use disorder for a study of an anti-psychotic medication to see it helps reduce substance cravings.
A Study To Compare Standard Chemotherapy To One Or More Investigational Drugs For Patients With Newly Diagnosed Aml
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.
Seeking boys aged 4-9 with Duchenne Muscular Dystrophy for a study of an investigational drug to prevent muscle damage.
Seeking women in the Worcester area who are pregnant or have recently given birth for a study of a breastfeeding support app.
This study is collecting tissue and information from pregnant women who are having cesarean births to gain a better understanding of how the uterus functions.
Seeking pregnant women with chronic hypertension, gestational hypertension or a history of hypertensive disorders of pregnancy for a brief survey of their experiences and approaches to healthy eating.
Pregnant women with either normal or high blood pressure sought for a study of the effects of high blood pressure during pregnancy. The study will assess whether future cardiovascular disease or serious pregnancy complications like preeclampsia can be better detected & prevented.
Pregnant women who are in their late 2nd to 3rd trimester who have high blood pressure are sought for a study to develop a screening test for preeclampsia in pregnant women. We will collect samples of your blood, urine, and saliva to see if we can detect levels of a protein that would help accurately predict who will get preeclampsia.
Seeking men and women with vitiligo for a study of the drug Metformin to see if it is safe and effective in returning normal skin color to white spots for people with vitiligo.
Seeking healthy adult volunteers or adults who has had skin allergy patch testing in the past for a study of how anti-inflammatory therapies work in inflamed skin.
Seeking males and females with Vitiligo to learn more about whether they are more or less likely to have increased complications related to vision and hearing.
Seeking children and adults with an autoimmune skin disease such as vitiligo, atopic dermatitis, alopecia areata, lupus, psoriasis, or scleroderma, and adult healthy volunteers willing to donate skin and blood for a study of autoimmune diseases of the skin.
We are studying how skin diseases occur in the skin, including how immune cells choose to initiate disease as well as what causes them to enter the skin.
Seeking people aged 6 and older with wounds caused by recessive dystrophic epidermolysis bullosa (RDEB) for a study of an investigational gene therapy.
Seeking people who need immediate care for frostbite for a study of an experimental method to rewarm frostbitten skin.
Seeking children under 18 years of age and healthy volunteers from 6 to 18 to study the skin immune system.
Seeking men and women with vitiligo for a study of an investigational drug to see if it is safe and effective in returning normal skin color to white spots for people with vitiligo.
Seeking men and women with or without an inflammatory skin disease ( such as cutaneous lupus erythematosus, dermatomyositis, atopic dermatitis, alopecia areata, scleroderma, eczema, psoriasis, vitilago, or drug hypersensitivity) for a study to learn more about skin diseases and their response to light.
Seeking men and women who take blood thinning medication and who will have Mohs surgery to remove skin cancer cells for a study of an investigational drug to reduce bleeding during surgery.
Seeking men and women 18 years of age or older who have had a stroke caused by bleeding in their brain to help determine is a new drug called recombinant factor VIIa (rFVIIa) can improve outcomes compared to a placebo when added to the standard care provided after a stroke.
Seeking men and women 18-85 years of age who have had an acute ischemic stroke caused by blood clots in the brain to evaluate a new device that is intended to remove these clots.
Comparing The Effects Of Different Levels Of Nursing Care Monitoring For Patients With Acute Ischemic Stroke (Optimist)
Men and women over 18 years old who have a diagnosis of acute ischemic stroke (AIS) and have been given intravenous thrombolysis (IVT) treatment.
Seeking men and women over 18 years of age who have had a stroke within the past 24 hours for the study of an investigational device.
Seeking men and women aged 18 and older for a study of sensors worn on or applied to the skin to measure pain.
Seeking men and women who will be admitted to the minimally invasive surgery service at UMass Memorial for a study of how walking after surgery helps with healing.
Seeking children who have been referred for outpatient ear surgery for a study comparing two drugs for managing pain and preventing emergence delirium when they are waking up from anesthesia following surgery.
Seeking men and women whose doctor has scheduled them for surgery to repair a colovesical fistula (CVF) for a study of the timing of foley catheter removal following surgery.
Seeking men and women aged 18-85 whose degenerative disc disease or spondylolisthesis requires spinal fusion surgery with bone grafting for a study of a synthetic bone graft.
A Study Looking To Reduce The Rate Of Postoperative Urinary Retention Rates In Men Who Have Had Thoracic Surgery (Pour)
Seeking men 60 years of age or older who will undergo inpatient thoracic surgery.
Seeking men and women aged 65 or older who have been discharged from the hospital within the past month for a survey of their health and use of healthcare following their discharge from the hospital.
Seeking men and women aged 18 and older who will be undergoing endovascular surgery to treat and aneurysm or blockage in their artery for a study to improve imaging needed for the surgery.
Seeking men and women who will be undergoing surgery or being cared for in an intensive care unit and who will require an intra-arterial catheter for a study of a investigational device similar to a wristwatch to continuously monitor blood pressure.
Seeking men and women, 18-80 years of age, who have experienced blunt head trauma with loss of consciousness for study of a new device to detect traumatic brain injury through blood testing.
Seeking adult men and women who have a wound that their medical provider has recommended be treated with a surgical procedure.
A Study Of An Investigational Drug In Subjects With Moderately To Severely Active Ulcerative Colitis.
Seeking Men and Women over 18 years of age with moderately to severely active ulcerative colitis for participation in a study of an investigational product called Efavaleukin Alfa