Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
52 Studies found
Seeking male and female children ranging from 0-18 months of age diagnosed with non-high risk neuroblastoma.
This study is looking at using different experimental treatment methods for children diagnosed with Acute Myeloid Leukemia (AML) and Down Syndrome (DS) based on how well they respond to their first treatment.
This study is for patients who may have neuroblastoma, a tumor of nerve cells typically found in the stomach, chest or neck of young children. This is a data and sample collection study to help us better understand this disease.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Volunteers who are participating in the NMTRC014 research study for treatment of neuroblastoma survivors who are in remission are sought for a research study of how the study drug is absorbed into the the body.
Seeking people aged 3 to 25 with newly-diagnosed high-grade glioma whose brain tumor has been genetically tested to show that it does not have the H3, K27M and BRAF mutations for a study of an investigational drug. The study will compare whether adding the investigational drug to radiation and maintenance therapy is better than the usual treatment.
Study Of An Investigational Drug For Relapsed Or Refractory Cd22+ B-Acute Lymphoblastic Leukemia (B All)
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
Seeking men and women who are or have been smokers and are at greater risk for lung cancer for a study to improve lung cancer screening
Study Of Chemotherapy For Children And Young Adults With High-Risk B-Cell Acute Lymphoblastic Leukemia (B-All)
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Study Of An Investigational Drug Given Alone Or In Combination With A Standard Treatment For Myelofibrosis
Seeking men and women with myelofibrosis bone marrow cancer for a study of an investigational drug given alone or in combination with a standard treatment.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Seeking adult men & women whose tumor cells have a change in a gene called ALK that causes the cells to grow and spread.
This study is collecting tumor tissue, body fluids and blood samples from patients undergoing biopsies or surgery to gain a better understanding of different cancers.
This study is looking to compare different surgical options for treating patients with rectal cancer.
Seeking adults with rectal cancer requiring surgery for a study comparing an investigational surgery to the standard surgery technique
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Study Of An Investigational Drug For Metastatic Prostate Cancer That Is Resistant To Hormone Treatment
Seeking men whose prostate cancer has spread beyond their prostate despite treatment with androgen deprivation therapy (also known as castration resistant prostate cancer) for a study comparing the usual treatment to the usual treatment with an experimental drug on controlling the cancer.
We are seeking people whose liver cancer was removed through surgery and radiation therapy for a study of an investigational drug to assess if it prevents the cancer from returning
We are studying whether combining an investigational drug with standard chemotherapy and surgery is more effective than just the standard chemotherapy and surgery in treating bladder cancer.
Study Of Immunotherapy Alone Or In Combination With Chemotherapy For Advanced Nonsquamous Non-Small Cell Lung Cancer
Non-squamous non-small cell lung cancer patients whose cancer has been tested to be PD-L1 positive (a kind of tumor marker) sought for study comparing two usual approaches to treatment.
Seeking men and women aged 18 and older whose colon, peritoneal, or rectal cancer will be treated with surgery (resectable) for a study of an investigational drug to make the cancer cells glow under infrared light.
Addition Of An Investigational Drug To The Usual Treatment For Limited Stage Small Cell Lung Cancer (Ls-Sclc)
Men and women with limited-stage small cell lung cancer, which has not spread outside of their chest area sought for a study comparing how cancer responds when adding an investigational drug to the usual treatment for small cell lung cancer
Men and women with advanced HPV throat cancer sought for a study comparing the outcomes for people who get chemotherapy and radiation followed by experimental immunotherapy to those who get chemotherapy and radiation followed by observation.
Seeking men and women with pancreatic cancer for a study of an experimental device used along with chemotherapy to evaluate whether it decreases cancer cell growth.
Seeking men and women with locally advanced pancreatic cancer that can't be completely removed with surgery for a study of an investigational drug added to the standard chemotherapy.
Seeking men and women who have been diagnosed with melanoma skin cancer and will have surgery to remove it for a study of whether starting the experimental drug before surgery is better or worse than starting the drug after surgery.
Study Of The Addition Of An Investigational Drug To Treatment Following Stem Cell Transplant For Multiple Myeloma
Seeking men and women who have had stem cell transplant for their multiple myeloma for a study of an investigational drug to be added to the usual maintenance treatment.
Seeking women with advanced high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancers with high folate-receptor-alpha expression for a study comparing an investigational drug to chemotherapy.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Study Of The Safety And Efficacy Of An Investigational Drug For Inoperable Early Stage Non Small Cell Lung Cancer
Seeking men and women with early stage (I/IIA) non small cell lung cancer that can't be removed with surgery for a study of an experimental drug.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Seeking women diagnosed with low-grade serous cancer of the ovary or peritoneum for a study of an investigational drug to reduce the risk of the cancer progressing or returning.
Study Adding An Investigational Immunotherapy To Standard Treatment For Locally-Advanced Non-Small Cell Lung Cancer
Seeking men and women diagnosed with locally-advanced non-small cell lung cancer that can't be treated with surgery for a study of adding an investigational immunotherapy to the standard cancer treatment.
Seeking women with ovarian cancer that progressed after at least 4 cycles of treatment with platinum-based chemotherapy for a study of an investigational drug.
Study Of An Investigational Drug Combination For Advanced Ovarian, Fallopian Tube Or Peritoneal Cancer
Seeking women with advanced ovarian, fallopian tube or peritoneal cancer who have, or will have "debulking" surgery to remove as much of their cancer as possible for a study of an investigational drug given in combination with the usual post-surgery chemotherapy with paclitiaxel and carboplatin.
Seeking men and women whose metastatic non-small lung cancer (NSCLC) has progressed after platinum doublet chemotherapy and immunotherapy for a study of an investigational drug combination.
Seeking men and women whose non-squamous non small cell lung cancer (NSCLC) has progressed after chemotherapy for a study of an investigational drug alone or in combination with an immune drug compared to the usual chemotherapy treatment.
Seeking men and women with HER2-positive breast cancer for a study comparing the usual multi-drug chemotherapy to a single chemotherapy drug and HER-2 therapy.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeking men and women who have non-small cell lung cancer removed and the cancer tumor has a change in the gene called the PD-L1 gene for a study of an investigational immunotherapy drug added to the usual chemotherapy.
Seeking men and women scheduled for MRI imaging for a clinical breast exam for a study comparing two dyes injected to enhance MRI images.
Seeking men and women whose non-small cell lung cancer responded or remained stable to platinum-based chemotherapy and are currently taking pembrolizumab for a study of an investigational drug combination for maintenance therapy.
Seeking men and women over the age of 70 whose pancreatic cancer has spread to other parts of their body for a study comparing two different drug combination therapies.
Seeking men and women aged 18 and older with colon or rectal cancer than has spread to other parts of their body (metastatic) for a study of an investigational drug added to the standard chemotherapy treatment.
Seeking men and women with cancer (breast, head and neck, squamous cell carcinoma, lymphoma, pancreatic, liver, colon, lung, bile duct, chordoma of sacrum, or sarcoma) that has not responded to chemotherapy (refractory) for a study of an investigational drug.
Study Of An Investigational Drug Combination For Initial Treatment For Metastatic Non-Small Cell Lung Cancer
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women whose non-small cell lung cancer has spread or stopped responding to treatment and whose cancer has been tested and found to have a specific mutation in the KRAS gene known as KRAS (G12C) for a study of an investigational drug for targeted treatment against the KRAS (G12C) mutation.