Seeking adult men and women with HER2 positive breast cancer who have already received treatment to determine if a combination of different drugs is better than the usual treatment alone in preventing this cancer from returning.
55 Studies found
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking male and female children ranging from 0-18 months of age diagnosed with non-high risk neuroblastoma.
This study is looking at using different experimental treatment methods for children diagnosed with Acute Myeloid Leukemia (AML) and Down Syndrome (DS) based on how well they respond to their first treatment.
This study is for patients who may have neuroblastoma, a tumor of nerve cells typically found in the stomach, chest or neck of young children. This is a data and sample collection study to help us better understand this disease.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Volunteers who are participating in the NMTRC014 research study for treatment of neuroblastoma survivors who are in remission are sought for a research study of how the study drug is absorbed into the the body.
Seeking people aged 3 to 25 with newly-diagnosed high-grade glioma whose brain tumor has been genetically tested to show that it does not have the H3, K27M and BRAF mutations for a study of an investigational drug. The study will compare whether adding the investigational drug to radiation and maintenance therapy is better than the usual treatment.
Study Of An Investigational Drug For Relapsed Or Refractory Cd22+ B-Acute Lymphoblastic Leukemia (B All)
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
Seeking men and women who are or have been smokers and are at greater risk for lung cancer for a study to improve lung cancer screening
Study Of Chemotherapy For Children And Young Adults With High-Risk B-Cell Acute Lymphoblastic Leukemia (B-All)
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Seeking men and women aged 18 and older who have been diagnosed with intermediate, high, or very high risk myelodysplastic Syndrome for a study of an investigational drug added to standard treatment.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Seeking adult men & women whose tumor cells have a change in a gene called ALK that causes the cells to grow and spread.
This study is collecting tumor tissue, body fluids and blood samples from patients undergoing biopsies or surgery to gain a better understanding of different cancers.
This study is looking to compare different surgical options for treating patients with rectal cancer.
Seeking adults with rectal cancer requiring surgery for a study comparing an investigational surgery to the standard surgery technique
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Study Of An Investigational Drug For Metastatic Prostate Cancer That Is Resistant To Hormone Treatment
Seeking men whose prostate cancer has spread beyond their prostate despite treatment with androgen deprivation therapy (also known as castration resistant prostate cancer) for a study comparing the usual treatment to the usual treatment with an experimental drug on controlling the cancer.
We are seeking people whose liver cancer was removed through surgery and radiation therapy for a study of an investigational drug to assess if it prevents the cancer from returning
Study Of Immunotherapy Alone Or In Combination With Chemotherapy For Advanced Nonsquamous Non-Small Cell Lung Cancer
Non-squamous non-small cell lung cancer patients whose cancer has been tested to be PD-L1 positive (a kind of tumor marker) sought for study comparing two usual approaches to treatment.
Seeking men and women aged 18 and older whose colon, peritoneal, or rectal cancer will be treated with surgery (resectable) for a study of an investigational drug to make the cancer cells glow under infrared light.
Addition Of An Investigational Drug To The Usual Treatment For Limited Stage Small Cell Lung Cancer (Ls-Sclc)
Men and women with limited-stage small cell lung cancer, which has not spread outside of their chest area sought for a study comparing how cancer responds when adding an investigational drug to the usual treatment for small cell lung cancer
Men and women with advanced HPV throat cancer sought for a study comparing the outcomes for people who get chemotherapy and radiation followed by experimental immunotherapy to those who get chemotherapy and radiation followed by observation.
Seeking men and women with pancreatic cancer for a study of an experimental device used along with chemotherapy to evaluate whether it decreases cancer cell growth.
Study Of The Addition Of An Investigational Drug To Treatment Following Stem Cell Transplant For Multiple Myeloma
Seeking men and women who have had stem cell transplant for their multiple myeloma for a study of an investigational drug to be added to the usual maintenance treatment.
Seeking women with advanced high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancers with high folate-receptor-alpha expression for a study comparing an investigational drug to chemotherapy.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Study Adding An Investigational Immunotherapy To Standard Treatment For Locally-Advanced Non-Small Cell Lung Cancer
Seeking men and women diagnosed with locally-advanced non-small cell lung cancer that can't be treated with surgery for a study of adding an investigational immunotherapy to the standard cancer treatment.
Seeking women with ovarian cancer that progressed after at least 4 cycles of treatment with platinum-based chemotherapy for a study of an investigational drug.
Study Of An Investigational Drug Combination For Advanced Ovarian, Fallopian Tube Or Peritoneal Cancer
Seeking women with advanced ovarian, fallopian tube or peritoneal cancer who have, or will have "debulking" surgery to remove as much of their cancer as possible for a study of an investigational drug given in combination with the usual post-surgery chemotherapy with paclitiaxel and carboplatin.
Seeking men and women whose non-squamous non small cell lung cancer (NSCLC) has progressed after chemotherapy for a study of an investigational drug alone or in combination with an immune drug compared to the usual chemotherapy treatment.
Seeking men and women with HER2-positive breast cancer for a study comparing the usual multi-drug chemotherapy to a single chemotherapy drug and HER-2 therapy.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeking men and women scheduled for MRI imaging for a clinical breast exam for a study comparing two dyes injected to enhance MRI images.
Seeking men and women whose non-small cell lung cancer responded or remained stable to platinum-based chemotherapy and are currently taking pembrolizumab for a study of an investigational drug combination for maintenance therapy.
Seeking men and women over the age of 70 whose pancreatic cancer has spread to other parts of their body for a study comparing two different drug combination therapies.
Seeking men and women aged 18 and older with colon or rectal cancer than has spread to other parts of their body (metastatic) for a study of an investigational drug added to the standard chemotherapy treatment.
Study Of An Investigational Drug Combination For Initial Treatment For Metastatic Non-Small Cell Lung Cancer
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Study Of An Investigational Drug Combination Following Surgery For Newly Diagnosed High-Risk Endometrial Cancer
Seeking women with newly diagnosed high-risk endometrial cancer that will be treated with surgery to remove the cancer for a study of an investigational drug given in combination with chemotherapy.
Seeking men and women with hormone receptor positive/ human epidermal growth factor receptor 2-negative (HR+/HER2-) locally advanced inoperable or metastatic breast cancer for a study of an investigational drug combination.
Seeking men and women whose non-small cell lung cancer has spread or stopped responding to treatment and whose cancer has been tested and found to have a specific mutation in the KRAS gene known as KRAS (G12C) for a study of an investigational drug for targeted treatment against the KRAS (G12C) mutation.
Seeking adult men and women with chronic graft versus host disease for a study of Axatilimab at 3 different doses.
A Study Comparing Medications In Patients 70 Years Of Age Or Younger With Untreated Mantle Cell Lymphoma
Seeking men and women 70 years of age or younger with untreated mantle cell lymphoma (MCL) to help determine which combination of cancer drugs most effectively treats their (MCL).
Seeking men and women 18 years of age and older who have chronic myeloid leukemia (CML) in chronic phase (CP) with and without the T315I mutation, to determine how well the treatment with asciminib works compared to previously used therapies.
Study Of An Investigational Drug Combination For Microsatellite Stable Recurrent Or Persistent Endometrial Cancer
Seeking women with microsatellite stable (MSS) recurrent or persistent endometrial cancer (EC) that has been treated with between one and three different types of chemotherapy for a study of an investigational drug combination to prevent the cancer from progressing.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
Seeking men and women who have been diagnosed since January 1, 2020, with metastatic non-small cell lung cancer and have been or will be treated with immunotherapy, chemotherapy or a combination of the two for a study to develop a tool to help guide treatment decisions.
Seeking men and women over 18 years old with HER2 negative gastric cancer for a study comparing chemotherapy plus investigational drugs to chemotherapy alone.
A Study To Compare Standard Chemotherapy To One Or More Investigational Drugs For Patients With Newly Diagnosed Aml
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.