Study Of An Investigational Drug For Nonrelapsing Secondary Progressive Multiple Sclerosis
Seeking men and women aged 18-60 years old with secondary progressive multiple sclerosis (MS) with no relapses (nrSPMS) for a study of an investigational drug
34 Studies found
Brain and Spinal Cord Diseases
Brain and Spinal Cord Diseases
Study Using Voice Recordings To Screen For Cognitive Impairment
Seeking people aged 65 and older for a study of a digital screening tool for mild cognitive impairment using audio recordings.
Healthy Volunteers Wanted.
Brain and Spinal Cord Diseases
Study Of An Investigational Drug For Primary Generalized Tonic-Clonic Seizures
Seeking people aged 12 and older with epilepsy who likely have primary generalized tonic-clonic seizure (PGTCS) for a study of an investigational drug.
Brain and Spinal Cord Diseases
Study Of An Investigational Drug For Symptomatic Neurogenic Orthostatic Hypotension
Seeking men and women with multiple system atrophy and experience dizziness or feeling faint due to neurogenic orthostatic hypotension for a study of an investigational drug.
Brain and Spinal Cord Diseases
Study Of An Investigational Device To Prevent Epileptic Seizures
Seeking people aged 9 and older who have epilepsy with focal seizures that has not responded to treatment for a study of an investigational device
Brain and Spinal Cord Diseases
Development Of An Mri Technique To Improve Brain Imaging
Seeking men and women aged 18 and older for a study of a device to help develop a Magnetic resonance imaging (MRI) technique to improve scans of the brain.
Healthy Volunteers Wanted.
Brain and Spinal Cord Diseases
Study Of A Digital Assessment To Screen For Cognitive Impairment In Older Adults
Seeking men and women over the age of 65 for a study of an investigational device to screen for cognitive impairment.
Healthy Volunteers Wanted.
Brain and Spinal Cord Diseases
A Study To Look At What Makes People Interested In Being A Part Of Parkinson's Disease Research (Fire-Up Pd)
Seeking men and women 18 years of age or older to complete surveys to help determine how people decide to participate in Parkinson's disease research
Brain and Spinal Cord Diseases
Gene Therapy Study For Adults With Adrenomyeloneuropathy
Seeking men and women with Adrenomyeloneuropathy for a gene therapy study to try and correct gene defects so that nerve cells can create proteins needed to prevent damage to spinal cord cells and nerves.
Brain and Spinal Cord Diseases
Study Of The Long Term Safety Of Ocrelizumab Treatment For People With Multiple Sclerosis (Ms)
Seeking women and men who have started ocrelizumab treatment for their Multiple Sclerosis (MS) within the past month or people whose MS is being being treated with therapies other than ocrelizumab for a study looking at the incidence of cancer in the future.
Brain and Spinal Cord Diseases
An Study Of Multiple Sclerosis At The University Of Massachusetts (Optimum)
This is a registry to collect medical record information from people living with Multiple Sclerosis (MS) to better understand the disease and develop new treatments
Brain and Spinal Cord Diseases
Study Of Spectral Imaging To Ct Scan Of The Brain To Detect Early Indicators Of Stroke
Seeking men and women who have been referred for minimally invasive endovascular treatment for aneurysm, stroke or arterio-venous malformations at the UMass Memorial Neurointerventional Radiology (NIR) angiosuite for a study comparing different imaging techniques.
Brain and Spinal Cord Diseases
Study Of An Investigational Device Worn On The Ear To Detect And Predict Epileptic Seizures
Seeking patients of the UMass Memorial Epilepsy Monitoring Unit aged 18 and older for a study of an investigational device to detect and predict epileptic seizures.
Brain and Spinal Cord Diseases
Study Of An Investigational Drug For People Receiving Disease Modifying Therapy For Relapsing Multiple Sclerosis
Seeking men and women aged 18 to 65 with relapsing multiple sclerosis who have either not started, or have discontinued treatment with a disease modifying therapy for a study of an investigational drug.
Brain and Spinal Cord Diseases
Study Of An Investigational Drug For Non-Active Secondary Progressive Multiple Sclerosis
Seeking people aged 18-75 with Non-Active Secondary Progressive Multiple Sclerosis for a study of an investigational drug given as a nasal spray.
Brain and Spinal Cord Diseases
Study Of Deep Brain Stimulation Effect On Voice For People Being Treated For Essential Tremor
Seeking men and women with dystonia and essential tremor undergoing deep brain stimulation (DBS) for a study to better understand laryngeal dystonia (LD) and voice tremor (VT), which are neurological conditions causing abnormal voice and speech control.
Brain and Spinal Cord Diseases
Study Comparing Discontinuation Versus Continuous Use Of Drug For Multiple Sclerosis
Seeking men and women diagnosed with Multiple sclerosis (MS) within the past 2 years for a study of whether ocrelizumab (study drug) can be used for a period of time rather than permanently and still control your early relapsing MS disease activity.
Brain and Spinal Cord Diseases
Study Of Use Of A Cpap Machine Following Stroke Or Transient Ischemic Attach (Tia)
Seeking men and women who have had a recent stroke or transient ischemic attach (TIA) often called a "mini-stroke" for a study of the benefits of using a continuous positive airway pressure (CPAP) machine while sleeping.
Brain and Spinal Cord Diseases
Study Comparing Anticoagulants To Prevent Stroke In People Who Have A History Of Brain Hemorrhage
Seeking men and women with atrial fibrillation and a recent brain hemorrhage causing increased risk for stroke for a study of blood thinners to reduce risk of stroke.
Brain and Spinal Cord Diseases
Study Of An Experimental Drug For Multiple Sclerosis That Hasn't Responded To Previous Treatment
Seeking men and women with multiple sclerosis (MS) that hasn't responded to previous treatment for a study of an experimental drug.
Brain and Spinal Cord Diseases
Collection And Study Of Blood Clots Removed During Treatment For Stroke
Seeking men and women whose doctor has recommended treatment for an acute ischemic stroke for a study collecting blood clots and medical information to better understand how to treat and prevent acute ischemic stroke.
Brain and Spinal Cord Diseases
Study Of The Use Of Statins After An Intracerebral Hemorrhage
Seeking men and women aged 50 and older who have had bleeding in the brain (brain hemorrhage) for a study comparing continuing or stopping statin drug use treatment on the risk of having another brain hemorrhage.
Brain and Spinal Cord Diseases
Registry To Study Genetic Origins Of Multiple Sclerosis
Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.
Healthy Volunteers Wanted.
Brain and Spinal Cord Diseases
Speech And Communication Changes In Parkinson’S Disease
Seeking people with Parkinson's disease and healthy volunteers for a study of how speech changes depending on PD symptoms, effects of medication and genetics.
Healthy Volunteers Wanted.
Brain and Spinal Cord Diseases
Study Of Sleep Apnea In People With Multiple Sclerosis
Seeking men and women with multiple sclerosis for a study of how common sleep apnea is and whether sleep apnea affects MS symptoms.
Brain and Spinal Cord Diseases
Study Of Multiple Investigational Drugs To Prevent Progression Of Amyotrophic Lateral Sclerosis (Als)
Seeking men and women with Amyotrophic Lateral Sclerosis (ALS) to participate in a research trial to test several different investigational treatments.
Brain and Spinal Cord Diseases
Study Of An Investigational Stem Cell Transplant For Treatment Resistant Relapsing Multiple Sclerosis
Seeking men and women whose multiple sclerosis has remained active despite treatment for a study comparing blood stem cell transplantation to other available treatments for multiple sclerosis.
Brain and Spinal Cord Diseases
Study Of The Effects Of Hospital Interventions Just After A Traumatic Brain Injury Affects Long-Term Outcome
Seeking men and women aged 18 and older who have been admitted to the hospital intensive care unit following a traumatic brain injury for a study of how care received in the hospital impacts long-term recovery.
Brain and Spinal Cord Diseases
Observational Study Of People Taking Cladribine Tablets For Relapsing Multiple Sclerosis
Seeking men and women with relapsing multiple sclerosis whose doctors has decided to start treatment with clabridine tablets because other pills were not working well.
Brain and Spinal Cord Diseases
A Study Comparing Two Ways Of Treating Patients With Brain Injury
This study is enrolling men and women who have had a traumatic brain injury in order to compare outcomes when medical care is delivered based on either monitoring the pressure in the brain or monitoring both the pressure in the brain and the amount of oxygen in the brain.
Brain and Spinal Cord Diseases
Traditional Versus Early Therapy For Multiple Sclerosis (Treat-Ms) Trial
Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.
Heart and Blood Vessel Diseases
Study Looking At Safety And Effectiveness Of An Approved Device To Treat A Weakness In A Blood Vessel In The Brain
Seeking men and women 18 years of age or older who have been diagnosed with a specific type brain aneurysm for study of the long term safety of an approved device (WEB®) intended to treat this issue.
Heart and Blood Vessel Diseases
Study Of An Investigational Device To Treat A Weakness In A Blood Vessel In The Brain (Citadel)
Seeking men and women 18 to 80 years of age who have been diagnosed with a specific type brain aneurysm for study of an investigational device intended to treat this issue.
Heart and Blood Vessel Diseases
Registry Of People At Risk For Heart Disease To Study Potential Causes Of Heart Attacks And Strokes
Volunteers who are at risk for having heart disease, taking aspirin, and will be or have already undergone a cardiac catheterization sought for a study of how the body makes blood clots and its effect on the risk for heart attack and stroke.