Seeking adults with metastatic or Cholangiocarcinoma that can't be removed through surgery and hasn't responded to therapy for a study of an investigational drug for bile duct cancer.
Seeking adult cancer survivors for a study of a physical activity program
Seeking men, women, and children to participate in a trial looking at a combination of drugs for use in treating a type of cancer called rhabdomyosarcoma (RMS).
Seeking people aged 5-60 newly diagnosed with early (Stage I or II) Hodgkin lymphoma that has not yet been treated for a study comparing the effect of adding immunotherapy to the standard chemotherapy to the standard chemotherapy alone.
Seeking UMass Memorial patients who are current or former smokers for a study about lung cancer screening
Seeking people with Mycosis Fungoides for a study to develop a test for Mycosis Fungoides.
Seeking women scheduled for a routine screening mammogram for a study comparing Artificial Intelligence (AI) software to standard guidelines for predicting breast cancer risk.
Seeking men and women who have been referred for follow-up imaging after a positive CT scan screen for lung cancer for a study of a blood test for early detection of lung cancer.
Seeking people aged up to 21 years for a study of decreasing the length of chemotherapy treatment for people with low risk rhabdomyosarcoma and increasing the length of chemotherapy treatment for people with high risk rhabrhabdomyosarcoma.
Seeking men and women with metastatic cancer that has spread to their brain and progressed or grew back after treatment for a study of an investigational immunotherapy drug based on the gene type and source of the original cancer to prevent growth of metastatic tumors in the brain.
Seeking men and women whose meningioma (cancer of the brain covering) has gotten bigger or grew back after treatment for a study of whether cancer drugs targeting tumors based on their genetics is better, the same, or worse than the standard treatment for meningiomas.
Seeking men and women who have been diagnosed since January 1, 2020, with metastatic non-small cell lung cancer and have been or will be treated with immunotherapy, chemotherapy or a combination of the two for a study to develop a tool to help guide treatment decisions.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Seeking men and women who have had a lung nodule detected during imaging for collection of nasal swab and blood samples.
Seeking people aged 30 and younger newly diagnosed with diffuse anaplastic Wilms tumor, a type of cancer that occurs in the kidney, for a study of experimental treatment regimen because no standard treatment regimen currently exists.
Seeking men and women who are current smokers for a study of motivational text messages to help people stop smoking.
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking men and women aged 18 and older whose colon, peritoneal, or rectal cancer will be treated with surgery (resectable) for a study of an investigational drug to make the cancer cells glow under infrared light.
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking men and women newly diagnosed with cancer for a study using artificial intelligence to create a more easily understood treatment plan summary.
Seeking men and women undergoing blood or bone marrow transplants, cord blood transplants or other cell therapy work for a collection of blood samples for future research
Seeking adults newly diagnosed with incidental gallbladder cancer for a study comparing chemotherapy treatment with gemcitabine and cisplatin before vs. after cancer removal surgery.
Seeking people with early-stage endometrial cancer for a study comparing radiation therapy and surgery to surgery alone for early-stage endometrial cancer treatment.
Seeking women with newly diagnosed early stage (I or II) uterine leiomyosarcoma for a study of whether taking an investigational drug following surgery is better than not taking the drug at preventing the cancer from returning.
Seeking adults with locally advanced non-small cell lung cancer for a study of adding radiation therapy to standard treatment for non-small cell lung cancer that cannot be treated by surgery (inoperable).
Seeking adults aged 70 and older with stage IIIB-IV lung cancer for a study comparing immunotherapy and chemotherapy to immunotherapy alone.
Seeking adults with Acute Myeloid Leukemia with an NPM1 mutation or KMT2A rearrangement for a study of an investigational drug to be used in combination with other chemotherapy drugs.
Seeking adults with early stage triple negative breast cancer for a study comparing a shorter chemo-immunotherapy to the usual therapy.
Seeking people with small cell lung cancer that has spread to other parts of the body (metastatic) for a study of whether adding radiation therapy to the usual treatment is better, worse or the same as the usual treatment alone following chemo-immunotherapy.
Seeking adults whose Multiple Myeloma has returned after treatment (Relapsed or Refractory) for a study of an investigational drug combination.
Seeking adults whose non-small Cell Lung Cancer has spread to other parts of their body (Metastatic) and who have not yet been treated for metastatic non-small cell lung cancer for a study of an investigational drug combination.
Seeking women whose endometrial cancer has previously been treated with platinum-based chemotherapy and immunotherapy for a study of an investigational drug.
Seeking men and women with a specific form of lung cancer to test if a combination of two specific drugs is beneficial.
Seeking men and women whose high-risk, non-muscle invasive bladder cancer has not spread to the muscle for a study comparing the standard Bacillus Calmette-Guerin (BCG) immunotherapy to an investigational chemotherapy drug combination.
Seeking adults whose triple-negative breast cancer remained following surgery and pre-surgery treatment for a study of an investigational drug.
Seeking adults with Stage III or IV melanoma skin cancer that will be treated with surgery for a study of an investigational drug combination.
Seeking men and women with colorectal cancer who will undergo colorectal surgery to remove part of their colon or rectum for a study of the healing process
Seeking men and women who have been diagnosed with lung cancer and plan to have surgery as part of their treatment for a study on improving health through exercise, diet, and stress management before surgery.
Seeking women with ovarian cancer, fallopian tube or primary peritoneal cancer that has returned or has stopped responding to previous treatment for a study testing an investigational drug for tumors expressing a protein know as folate receptor alpha (FOLR1).
Seeking men and women with advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes for a study comparing targeted drug combinations
Seeking men and women with stage III or IV head and neck cancer for a study comparing two treatment options following tumor removal surgery.
Seeking people with locally advanced or metastatic platinum-resistant ovarian, endometrial, or urothelial cancer for a study of an investigational drug.
Seeking people aged 12 and older whose previous treatment has failed for a study of an investigational drug for locally advanced or metastatic cancer of the bladder, urinary tract, and other solid tumors
Seeking people who have who have already taken endocrine therapy for two to five years for their early-stage ER+/HER2- breast cancer and have a higher-than-average risk for their cancer to return for a study to compare the investigational drug to standard hormone therapy.
Seeking men and women who have a type of cancer that affects the B-cells (a type of white blood cells) in your blood that has not responded to, or who could not tolerate, the standard treatments normally given for this type of cancer for a study of an investigational drug.
Seeking men and women who have Multiple Myeloma (MM) and will undergo Autologous Stem Cell Transplant (ASCT) as a form of treatment for a study of an investigational drug to help collect blood stem cells.
IRONMAN Registry aims to collect detailed information about the participants in the study at the time of enrollment and to follow their medical care to better understand what treatments work and where there are unmet needs in their treatment.
Seeking men and women aged 18-65 years whose large B-Cell lymphoma has not responded or come back after treatment for a study of an investigational drug combination.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.