Seeking people with confirmed gastric, esophageal or gastroesophageal malignancy undergoing a cancer stage evaluation to plan treatment for a study of an diagnostic test for metastatic disease.
Seeking adults with Pancreatic Ductal Adenocarcinoma who have a PET scan scheduled in the next 3 weeks for treatment planning for a study of an investigational diagnostic test for metastatic disease.
Looking for kids, teens, and young adults with With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)for a study of an investigational drug combination help people feel better, have fewer side effects, and prevent cancer from returning.
Seeking adults with Chronic Primary Immune Thrombocytopenia (ITP) which has not responded to previous treatment for a study of an investigational drug injection to improve platelet counts.
Seeking people aged 30 and younger for a study using risk factors including cancer stage to determine one of six different treatments regimes for children and young adults with Favorable Histology Wilms Tumors Kidney Cancer.
Seeking adult cancer survivors for a study of a physical activity program
Seeking people aged 5-60 newly diagnosed with early (Stage I or II) Hodgkin lymphoma that has not yet been treated for a study comparing the effect of adding immunotherapy to the standard chemotherapy to the standard chemotherapy alone.
Seeking UMass Memorial patients who are current or former smokers for a study about lung cancer screening
Seeking women scheduled for a routine screening mammogram for a study comparing Artificial Intelligence (AI) software to standard guidelines for predicting breast cancer risk.
Seeking men and women who have been referred for follow-up imaging after a positive CT scan screen for lung cancer for a study of a blood test for early detection of lung cancer.
Seeking people aged up to 21 years for a study of decreasing the length of chemotherapy treatment for people with low risk rhabdomyosarcoma and increasing the length of chemotherapy treatment for people with high risk rhabrhabdomyosarcoma.
Seeking men and women who have had a lung nodule detected during imaging for collection of nasal swab and blood samples.
Seeking people aged 30 and younger newly diagnosed with diffuse anaplastic Wilms tumor, a type of cancer that occurs in the kidney, for a study of experimental treatment regimen because no standard treatment regimen currently exists.
Seeking men and women who are current smokers for a study of motivational text messages to help people stop smoking.
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking adults with newly diagnosed Multiple Myeloma (NDMM) that can't be treated with autologous stem cell transplantation for a study of an investigational drug called Belantamab Mafodotin added to treatment with Lenalidomide and Dexamethasone.
Seeking men and women with metastatic non-small cell lung cancer with high PD-L1 that has not previously been treated for a study comparing an investigational drug to the usual treatment.
Seeking adults with advanced or metastatic gastrointestinal stromal tumor (GIST) with a documented KIT gene mutation for a study of an investigational drug taken in combination with ripretinib.
Looking for adults with advanced lung cancer who have had platinum chemotherapy and immunotherapy before. This study compares usual medicine with or without a new medicine called cemiplimab.
Seeking women with advanced epithelial ovarian, primary peritoneal, or fallopian tube cancer for a study of different dosages and dosing schedules of an investigational drug.
Seeking adults with advanced non-small cell lung cancer that has extra copies of the MET gene for a study of an investigational study drug to lower the growth or spread of cancer.
Seeking people with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) for a study collecting blood or bone marrow to test for biomarkers to use to match them to a myeloid cancer treatment clinical trial opportunity.
Seeking men and women newly diagnosed with cancer for a study using artificial intelligence to create a more easily understood treatment plan summary.
Seeking men and women who have been diagnosed with metastatic non-small cell lung cancer with STK11, KEAP1, or KRAS genetic mutations and have not yet started treatment for a study comparing an investigational drug combination to the standard drug combination.
Seeking men and women undergoing blood or bone marrow transplants, cord blood transplants or other cell therapy work for a collection of blood samples for future research
Seeking people with early-stage endometrial cancer for a study comparing radiation therapy and surgery to surgery alone for early-stage endometrial cancer treatment.
Seeking women with newly diagnosed early stage (I or II) uterine leiomyosarcoma for a study of whether taking an investigational drug following surgery is better than not taking the drug at preventing the cancer from returning.
Seeking adults with locally advanced non-small cell lung cancer for a study of adding radiation therapy to standard treatment for non-small cell lung cancer that cannot be treated by surgery (inoperable).
Seeking adults with Acute Myeloid Leukemia with an NPM1 mutation or KMT2A rearrangement for a study of an investigational drug to be used in combination with other chemotherapy drugs.
Seeking adults with early stage triple negative breast cancer for a study comparing a shorter chemo-immunotherapy to the usual therapy.
Seeking people with small cell lung cancer that has spread to other parts of the body (metastatic) for a study of whether adding radiation therapy to the usual treatment is better, worse or the same as the usual treatment alone following chemo-immunotherapy.
We are looking for adults with advanced bladder cancer that has spread and whose cancer cells have a protein called HER2. Some participants will have had previous treatments for their cancer, while others have not had treatment before. The study will test a new drug alone or combined with another medicine to see if it helps shrink tumors and is safe.
Seeking men and women with a specific form of lung cancer to test if a combination of two specific drugs is beneficial.
Seeking adults whose triple-negative breast cancer remained following surgery and pre-surgery treatment for a study of an investigational drug.
Seeking adults with newly diagnosed Multiple Myeloma for a study of an investigational drug for maintenance therapy following stem cell transplant.
Seeking men and women with advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes for a study comparing targeted drug combinations
Seeking men and women who have a type of cancer that affects the B-cells (a type of white blood cells) in your blood that has not responded to, or who could not tolerate, the standard treatments normally given for this type of cancer for a study of an investigational drug.
IRONMAN Registry aims to collect detailed information about the participants in the study at the time of enrollment and to follow their medical care to better understand what treatments work and where there are unmet needs in their treatment.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.
Seeking women who get their routine pap smear screening at UMass Memorial Healthcare for a study collecting cervical and/or vulvar swabs to test an investigational device to screen for HPV associated with cervical and vulvar cancers.