This study is looking at using different experimental treatment methods for children diagnosed with Acute Myeloid Leukemia (AML) and Down Syndrome (DS) based on how well they respond to their first treatment.
12 Studies found
Study Of An Investigational Drug For Relapsed Or Refractory Cd22+ B-Acute Lymphoblastic Leukemia (B All)
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
Study Of Chemotherapy For Children And Young Adults With High-Risk B-Cell Acute Lymphoblastic Leukemia (B-All)
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Study Of An Investigational Drug For Advanced Relapsed, Refractory, Or Resistant Hematological (Blood) Cancer
Seeking men and women with advanced relapsed, refractory, or resistant hematological (blood) cancer with an IDH mutation that has not responded or stopped responding to prior treatment for participation in a study of an investigational drug.
Seeking men and women who have Myelofibrosis bone marrow cancer and are not going to have a stem cell transplant for a study of an investigational drug reduce spleen volume and improve symptoms of Myelofibrosis.
Study Of The Addition Of An Investigational Drug To Treatment Following Stem Cell Transplant For Multiple Myeloma
Seeking men and women who have had stem cell transplant for their multiple myeloma for a study of an investigational drug to be added to the usual maintenance treatment.
Study Of An Investigational Drug Added To Usual Treatment For Relapsed Or Refractory Multiple Myeloma
Seeking men and women whose multiple myeloma has returned or has not responded to their most recent treatment for a study adding an investigational drug to the usual treatment.
Study Of An Investigational Drug Combination For Relapsed Or Refractory Diffuse Large B-Cell Lymphoma
Seeking men and women aged 18-65 years whose large B-Cell lymphoma has not responded or come back after treatment for a study of an investigational drug combination.
Study Of An Investigational Drug For Maintenance Therapy Following Remission Of Acute Myeloid Leukemia
Seeking men and women whose acute myeloid leukemia is in remission following an initial treatment with conventional chemotherapy for a study of an investigational drug for maintenance therapy
Seeking men and women with with Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia for a study of an investigational drug to reduce spleen volume.