Conquering Diseases

Study Of An Investigational Gene Therapy For Recessive Dystrophic Epidermolysis Bullosa

Description

Seeking people aged 6 and older with wounds caused by recessive dystrophic epidermolysis bullosa (RDEB) for a study of an investigational gene therapy.

Overview

Participants in this study will provide samples of their skin cells that will then be genetically engineered to allow the cells to make collagen. These cells will then be used to grow sheets of cells that will be placed onto the participants skin. Depending on the area of skin to be biopsied and treated, this may need to be done under general anesthesia.

What we're hoping for

We are studying whether an investigational gene therapy helps skin to start making collagen and be less likely to blister or wound for people with Recessive Dystrophic Epidermolysis Bullosa (RDEB)

Additional Information

ClinicalTrials.gov Identifier: NCT05725018

 Principal Investigator

Karen  Wiss, MD

UMass Memorial Health

 Study Contact

Dermatology  Research

774-455-4758

DermResearch@umassmed.edu

 Location

UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655

508-856-8989