Conquering Diseases

Cancer Therapy Risk-Reduction With Intensive Systolic Blood Pressure Management


Seeking men and women 18 years of age or older, with kidney or thyroid cancer who are taking medications that help stop the spread of these cancers to look at the effects of blood pressure and blood pressure monitoring related to these medications.


We are studying the relationship between certain medicines used to help stop certain types of cancers from growing and blood pressure. This type of medicine is known as an anti-angiogenic tyrosine kinase inhibitor (AA-TKI). These medicines can also affect the blood pressure. This study will explore the effects of blood pressure targets in patients receiving AA-TKIs.

What we're hoping for

The goal is to answer the following question: can lowering systolic blood pressure to less than 120mmHg be achieved, well tolerated and beneficial as compared to less than 140mmHg?

Additional Information Identifier: NCT04467021

 Principal Investigator

Kriti  Mittal, MD, MS

UMass Memorial Health

 Study Contact

The Cancer  Research Office



UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655