Conquering Diseases

Gene Therapy Study For Adults With Adrenomyeloneuropathy

Description

Seeking men and women with Adrenomyeloneuropathy for a gene therapy study to try and correct gene defects so that nerve cells can create proteins needed to prevent damage to spinal cord cells and nerves.

Overview

Participants in this study will be randomly assigned to receive either the gene therapy or a sham procedure (similar in everyway to the gene therapy, but no medication will be given). One in four participants (25%) will receive the sham procedure. After 24 months the participants who received the sham procedure will be offered the opportunity to get the investigational gene therapy.

What we're hoping for

We are studying whether the gene therapy is safe and effective in correcting gene defects so that nerve cells can create proteins needed to prevent damage to spinal cord cells and nerves.

Additional Information

ClinicalTrials.gov Identifier: NCT05394064

 Principal Investigator

Mehdi  Ghasemi, MD

UMass Chan Medical School

 Study Contact

Catherine  Douthwright

508-856-6491

Catherine.Douthwright@umassmed.edu

 Location

UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655

508-856-8989