Conquering Diseases

Study Of The Safety And Effectiveness Of A Investigational Booster Vaccine For Covid-19


Seeking men and women who have previously received two doses of the Moderna COVID-19 vaccine for a study of a booster vaccine that is slightly different than the original Moderna COVID-19 vaccine.


Participants in this study will be randomly assigned to get either the investigational booster vaccine at one of several dose levels or the standard dose of the Moderna vaccine. Participants will have up to 8 study visits over 13 months. Women of childbearing age will be asked to use birth control for approximately 5 months from the time they consent to be in the study.

What we're hoping for

We hope to evaluate the safety and effectiveness of a COVID-19 booster vaccine that his a slightly different structure than the vaccine that has received emergency use authorization from the FDA.

Additional Information Identifier: NCT05137236

 Principal Investigator

Jennifer P. Wang, MD

UMass Memorial Health Care

 Study Contact

Shestruma  Parajuli


UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655