Conquering Diseases

Study Of Investigational Vaccine To Prevent The Epstein-Barr Virus That Can Cause Mononucleosis


Seeking men and women aged 18 to 30 for a study of an investigational vaccine to prevent the Epstein-Barr virus, which is the main cause of infectious mononucleosis.


Participants in this study will receive one of three doses (low, medium or high) of the investigational vaccine or placebo. Over a year and a half participants will have about 15 office visits. On three of the office visits they will get injections of the investigational vaccine. The other follow-up visits will be to have their blood checked for antibodies to the Epstein Barr Virus. Participants will be asked to complete an electronic diary using a smartphone app.

What we're hoping for

We are hoping that the investigational vaccine will be safe and effective in creating antibodies in participants blood that will prevent infection by the Epstein-Barr virus which is the main cause of infectious mononucleosis.

Additional Information Identifier: NCT05164094

 Principal Investigator

Katherine  Luzuriaga, MD

University of Massachusetts Medical School

 Study Contact

Moderna  EBV Trial



UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655